Ruthenium Chemistry /
edited by Ajay Kumar Mishra, Lallan Mishra.
- First edition.
- 1 online resource
chapter 1 An Introduction to Ruthenium Chemistry / chapter 2 Ruthenium in Medicinal Chemistry / chapter 3 An Overview of Ruthenium Complexes as a Potential Sensing Agent / chapter 4 Ruthenium Compounds: A New Approach in Nanochemistry / chapter 5 Synthesis and Characterization of Copper-Ruthenium Composites / chapter 6 Orbital Tuning of Ruthenium Polyimine Complexes by Ligand Design: From Basic Principles to Applications / chapter 7 The Development of Ru(II)-p-Cymene Complexes with Pyridine Derivatives as Anti-Cancer Agents / chapter 8 Approaching Cancer Therapy with Ruthenium Complexes by Their Interaction with DNA / chapter 9 Ruthenium Aryl Sulfides Complexes / chapter 10 Tuning of Ruthenium - DMSO Complexes for Search of New Anticancer Agents / Lallan Mishra Ajay Kumar Mishra -- Dinorah Gambino Lucía Otero -- Goutam Kumar Patra Anupam Ghorai -- Pradeep Pratap Singha Ambikab -- Rasidi Sule Iakovos Sigalas Joseph Kwaku Ofori Asante Peter Apata Olubambi -- Joe Otsuki Guohua Wu Ryuji Kaneko Yayoi Ebata -- Nevenk Gligorijevć Sandra Aranđelović Katarina K. Jovanović Sanja Grgurić-Šipka Siniša Radulović -- Niraj Kumari Lallan Mishra -- Minu Gupta Bhowon Sabina Jhaumeer Laulloo -- Ruchi Gaur Lallan Mishra.
"This book will describe Ruthenium complexes as chemotherapeutic agent specifically at tumor site. It has been the most challenging task in the area of cancer therapy. Nanoparticles are now emerging as the most effective alternative to traditional chemotherapeutic approach. Nanoparticles have been shown to be useful in this respect. However, in view of organ system complicacies, instead of using nanoparticles as a delivery tool, it will be more appropriate to synthesize a drug of nanoparticle size that can use blood transport mechanism to reach the tumor site and regress cancer. Due to less toxicity and effective bio-distribution, ruthenium (Ru) complexes are of much current interest. Additionally, lumiscent Ru-complexes can be synthesized in nanoparticle size and can be directly traced at tissue level. The book will contain the synthesis, characterization, and applications of various Ruthenium complexes as chemotherapeutic agents. The book will also cover the introduction to chemotherapy, classification of Ru- complexes with respect to their oxidation states and geometry, Ruthenium complexes of nano size: shape and binding- selectivity, binding of ruthenium complexes with DNA, DNA cleavage studies and cytotoxicity.The present book will be more beneficial to researchers, scientists and biomedical. Current book will empower specially to younger generation to create a new world of ruthenium chemistry in material science as well as in medicines. This book will be also beneficial to national/international research laboratories, and academia with interest in the area of coordination chemistry more especially to the Ruthenium compounds and its applications."--Provided by publisher.
9781315110585 9781351616485
10.1201/9781315110585 doi
Catalysis.
Chemistry, Inorganic.
Ruthenium.
QD181.R9 / R88 2018
546.632 / R974
chapter 1 An Introduction to Ruthenium Chemistry / chapter 2 Ruthenium in Medicinal Chemistry / chapter 3 An Overview of Ruthenium Complexes as a Potential Sensing Agent / chapter 4 Ruthenium Compounds: A New Approach in Nanochemistry / chapter 5 Synthesis and Characterization of Copper-Ruthenium Composites / chapter 6 Orbital Tuning of Ruthenium Polyimine Complexes by Ligand Design: From Basic Principles to Applications / chapter 7 The Development of Ru(II)-p-Cymene Complexes with Pyridine Derivatives as Anti-Cancer Agents / chapter 8 Approaching Cancer Therapy with Ruthenium Complexes by Their Interaction with DNA / chapter 9 Ruthenium Aryl Sulfides Complexes / chapter 10 Tuning of Ruthenium - DMSO Complexes for Search of New Anticancer Agents / Lallan Mishra Ajay Kumar Mishra -- Dinorah Gambino Lucía Otero -- Goutam Kumar Patra Anupam Ghorai -- Pradeep Pratap Singha Ambikab -- Rasidi Sule Iakovos Sigalas Joseph Kwaku Ofori Asante Peter Apata Olubambi -- Joe Otsuki Guohua Wu Ryuji Kaneko Yayoi Ebata -- Nevenk Gligorijevć Sandra Aranđelović Katarina K. Jovanović Sanja Grgurić-Šipka Siniša Radulović -- Niraj Kumari Lallan Mishra -- Minu Gupta Bhowon Sabina Jhaumeer Laulloo -- Ruchi Gaur Lallan Mishra.
"This book will describe Ruthenium complexes as chemotherapeutic agent specifically at tumor site. It has been the most challenging task in the area of cancer therapy. Nanoparticles are now emerging as the most effective alternative to traditional chemotherapeutic approach. Nanoparticles have been shown to be useful in this respect. However, in view of organ system complicacies, instead of using nanoparticles as a delivery tool, it will be more appropriate to synthesize a drug of nanoparticle size that can use blood transport mechanism to reach the tumor site and regress cancer. Due to less toxicity and effective bio-distribution, ruthenium (Ru) complexes are of much current interest. Additionally, lumiscent Ru-complexes can be synthesized in nanoparticle size and can be directly traced at tissue level. The book will contain the synthesis, characterization, and applications of various Ruthenium complexes as chemotherapeutic agents. The book will also cover the introduction to chemotherapy, classification of Ru- complexes with respect to their oxidation states and geometry, Ruthenium complexes of nano size: shape and binding- selectivity, binding of ruthenium complexes with DNA, DNA cleavage studies and cytotoxicity.The present book will be more beneficial to researchers, scientists and biomedical. Current book will empower specially to younger generation to create a new world of ruthenium chemistry in material science as well as in medicines. This book will be also beneficial to national/international research laboratories, and academia with interest in the area of coordination chemistry more especially to the Ruthenium compounds and its applications."--Provided by publisher.
9781315110585 9781351616485
10.1201/9781315110585 doi
Catalysis.
Chemistry, Inorganic.
Ruthenium.
QD181.R9 / R88 2018
546.632 / R974