Nanomaterials for clinical applications : case studies in nanomedicines /
edited by Natassa Pippa and Costas Demetzos.
- Amsterdam : Elsevier, 2020.
- 1 online resource
- Micro and nano technologies .
- Micro & nano technologies. .
Includes index.
Front Cover -- Nanomaterials for Clinical Applications -- Copyright Page -- Contents -- List of contributors -- 1. Solid lipid nanoparticles in dermaceuticals -- 1.1 General introduction -- 1.2 Why solid lipid nanoparticles? -- 1.2.1 Formulation aspects -- 1.2.2 Physiological aspects -- 1.3 Evolution of lipidic nanoparticles from solid lipid nanoparticles to nanostructured lipid carriers -- 1.4 Cosmetic and topical applications of solid lipid nanoparticles -- 1.5 Skin penetration with solid lipid nanoparticles -- 1.6 Mechanism of drug penetration with solid lipid nanoparticles 1.7 Incorporation into semisolid vehicle -- 1.8 Case studies of successful topical delivery with lipidic nanoparticles -- 1.8.1 Delivery of antimicrobials -- 1.9 Delivery of agents for other skin diseases -- 1.9.1 Solid lipid nanoparticles for cosmetic applications -- 1.10 Conclusions -- References -- 2. Cyclodextrin-based drug delivery systems -- 2.1 Cyclodextrins-structure, physiochemical properties, and toxicological profile -- 2.2 Cyclodextrin inclusion complexes-formation, stability, and application in drug delivery -- 2.3 Cyclodextrin-based products in clinical practice 2.3.3.1 Cyclodextrins in control of obesity and hyperlipidemia -- References -- 3. Lipid vesicles for (trans)dermal administration -- 3.1 (Trans)dermal drug-delivery systems -- 3.1.1 Human skin barrier to xenobiotics -- 3.2 Lipid vesicles for breaching the skin barrier -- 3.2.1 Conventional liposomes -- 3.2.2 Transfersomes -- 3.2.3 Ethanol-based lipid vesicles -- 3.2.3.1 Ethosomes -- 3.2.3.2 Transethosomes -- 3.2.3.3 Other lipid vesicles -- 3.3 Liposomal formulation in clinics -- 3.3.1 Conventional liposomes -- 3.3.2 Transfersomes -- 3.3.3 Ethosomes -- 3.4 Final remarks -- References 4. Stimuli-responsive nanocarriers for drug delivery -- 4.1 Introduction -- 4.2 Types of stimuli -- 4.2.1 pH-responsive nanosystems -- 4.2.2 Thermoresponsive nanosystems -- 4.3 Development of chimeric stimuli-responsive liposomes with incorporated stimuli-responsive polymers -- 4.3.1 pH-responsive liposomes -- 4.3.2 Thermoresponsive liposomes -- 4.4 Thermotropic behavior of stimuli-responsive liposomes -- 4.4.1 Thermal analysis on pH-responsive liposomes -- 4.4.2 Thermal analysis of thermoresponsive liposomes -- 4.5 Physicochemical properties of stimuli-responsive liposomes
9780128168769 0128168765
GBC027244 bnb
019718644 Uk
Nanoparticles.
Nanoparticles
Nanoparticules.
Nanoparticles.
RS201.N35
620/.5
Includes index.
Front Cover -- Nanomaterials for Clinical Applications -- Copyright Page -- Contents -- List of contributors -- 1. Solid lipid nanoparticles in dermaceuticals -- 1.1 General introduction -- 1.2 Why solid lipid nanoparticles? -- 1.2.1 Formulation aspects -- 1.2.2 Physiological aspects -- 1.3 Evolution of lipidic nanoparticles from solid lipid nanoparticles to nanostructured lipid carriers -- 1.4 Cosmetic and topical applications of solid lipid nanoparticles -- 1.5 Skin penetration with solid lipid nanoparticles -- 1.6 Mechanism of drug penetration with solid lipid nanoparticles 1.7 Incorporation into semisolid vehicle -- 1.8 Case studies of successful topical delivery with lipidic nanoparticles -- 1.8.1 Delivery of antimicrobials -- 1.9 Delivery of agents for other skin diseases -- 1.9.1 Solid lipid nanoparticles for cosmetic applications -- 1.10 Conclusions -- References -- 2. Cyclodextrin-based drug delivery systems -- 2.1 Cyclodextrins-structure, physiochemical properties, and toxicological profile -- 2.2 Cyclodextrin inclusion complexes-formation, stability, and application in drug delivery -- 2.3 Cyclodextrin-based products in clinical practice 2.3.3.1 Cyclodextrins in control of obesity and hyperlipidemia -- References -- 3. Lipid vesicles for (trans)dermal administration -- 3.1 (Trans)dermal drug-delivery systems -- 3.1.1 Human skin barrier to xenobiotics -- 3.2 Lipid vesicles for breaching the skin barrier -- 3.2.1 Conventional liposomes -- 3.2.2 Transfersomes -- 3.2.3 Ethanol-based lipid vesicles -- 3.2.3.1 Ethosomes -- 3.2.3.2 Transethosomes -- 3.2.3.3 Other lipid vesicles -- 3.3 Liposomal formulation in clinics -- 3.3.1 Conventional liposomes -- 3.3.2 Transfersomes -- 3.3.3 Ethosomes -- 3.4 Final remarks -- References 4. Stimuli-responsive nanocarriers for drug delivery -- 4.1 Introduction -- 4.2 Types of stimuli -- 4.2.1 pH-responsive nanosystems -- 4.2.2 Thermoresponsive nanosystems -- 4.3 Development of chimeric stimuli-responsive liposomes with incorporated stimuli-responsive polymers -- 4.3.1 pH-responsive liposomes -- 4.3.2 Thermoresponsive liposomes -- 4.4 Thermotropic behavior of stimuli-responsive liposomes -- 4.4.1 Thermal analysis on pH-responsive liposomes -- 4.4.2 Thermal analysis of thermoresponsive liposomes -- 4.5 Physicochemical properties of stimuli-responsive liposomes
9780128168769 0128168765
GBC027244 bnb
019718644 Uk
Nanoparticles.
Nanoparticles
Nanoparticules.
Nanoparticles.
RS201.N35
620/.5