Analysis of Deterministic Cyclic Gene Regulatory Network Models with Delays (Record no. 53098)

000 -LEADER
fixed length control field 03264nam a22005895i 4500
001 - CONTROL NUMBER
control field 978-3-319-15606-4
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20200420221259.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 150225s2015 gw | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9783319156064
-- 978-3-319-15606-4
082 04 - CLASSIFICATION NUMBER
Call Number 519
100 1# - AUTHOR NAME
Author Ahsen, Mehmet Eren.
245 10 - TITLE STATEMENT
Title Analysis of Deterministic Cyclic Gene Regulatory Network Models with Delays
300 ## - PHYSICAL DESCRIPTION
Number of Pages XIII, 94 p. 15 illus. in color.
490 1# - SERIES STATEMENT
Series statement SpringerBriefs in Electrical and Computer Engineering,
505 0# - FORMATTED CONTENTS NOTE
Remark 2 Preface -- Introduction -- Basic Tools from Systems and Control Theory -- Functions with Negative Schwarzian Derivatives -- Deterministic ODE-Based Model with Time Delay -- Gene Regulatory Networks under Negative Feedback -- Gene Regulatory Networks under Positive Feedback -- Summary and Concluding Remarks -- References.
520 ## - SUMMARY, ETC.
Summary, etc This brief examines a deterministic, ODE-based model for gene regulatory networks (GRN) that incorporates nonlinearities and time-delayed feedback. An introductory chapter provides some insights into molecular biology and GRNs. The mathematical tools necessary for studying the GRN model are then reviewed, in particular Hill functions and Schwarzian derivatives. One chapter is devoted to the analysis of GRNs under negative feedback with time delays and a special case of a homogenous GRN is considered. Asymptotic stability analysis of GRNs under positive feedback is then considered in a separate chapter, in which conditions leading to bi-stability are derived. Graduate and advanced undergraduate students and researchers in control engineering, applied mathematics, systems biology and synthetic biology will find this brief to be a clear and concise introduction to the modeling and analysis of GRNs.
700 1# - AUTHOR 2
Author 2 �Ozbay, Hitay.
700 1# - AUTHOR 2
Author 2 Niculescu, Silviu-Iulian.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-3-319-15606-4
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type eBooks
264 #1 -
-- Cham :
-- Springer International Publishing :
-- Imprint: Birkh�auser,
-- 2015.
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-- text
-- txt
-- rdacontent
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-- computer
-- c
-- rdamedia
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-- online resource
-- cr
-- rdacarrier
347 ## -
-- text file
-- PDF
-- rda
650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1
-- Mathematics.
650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1
-- Gene expression.
650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1
-- System theory.
650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1
-- Biomathematics.
650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1
-- Control engineering.
650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1
-- Robotics.
650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1
-- Mechatronics.
650 14 - SUBJECT ADDED ENTRY--SUBJECT 1
-- Mathematics.
650 24 - SUBJECT ADDED ENTRY--SUBJECT 1
-- Systems Theory, Control.
650 24 - SUBJECT ADDED ENTRY--SUBJECT 1
-- Mathematical and Computational Biology.
650 24 - SUBJECT ADDED ENTRY--SUBJECT 1
-- Gene Expression.
650 24 - SUBJECT ADDED ENTRY--SUBJECT 1
-- Control, Robotics, Mechatronics.
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
-- 2191-8112
912 ## -
-- ZDB-2-ENG

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