3D Electro-Rotation of Single Cells (Record no. 84851)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04074nam a22005415i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-3-031-01666-0 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240730163648.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220601s2020 sz | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| ISBN | 9783031016660 |
| -- | 978-3-031-01666-0 |
| 082 04 - CLASSIFICATION NUMBER | |
| Call Number | 620 |
| 100 1# - AUTHOR NAME | |
| Author | Buonincontri, Guido. |
| 245 10 - TITLE STATEMENT | |
| Title | 3D Electro-Rotation of Single Cells |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. 2020. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Number of Pages | XVII, 101 p. |
| 490 1# - SERIES STATEMENT | |
| Series statement | Synthesis Lectures on Biomedical Engineering, |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Remark 2 | Acknowledgments -- Introduction -- Thick-Electrode DEP for Single-Cell 3D Rotation -- Opto-Electronic Integration of Thick-Electrode DEP Microfluidic Chip -- Summary and Outlook -- References -- Authors' Biographies. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Dielectrophoresis microfluidic chips have been widely used in various biological applications due to their advantages of convenient operation, high throughput, and low cost. However, most of the DEP microfluidic chips are based on 2D planar electrodes which have some limitations, such as electric field attenuation, small effective working regions, and weak DEP forces. In order to overcome the limitations of 2D planar electrodes, two kinds of thick-electrode DEP chips were designed to realize manipulation and multi-parameter measurement of single cells. Based on the multi-electrode structure of thick-electrode DEP, a single-cell 3D electro-rotation chip of "Armillary Sphere" was designed. The chip uses four thick electrodes and a bottom planar electrode to form an electric field chamber, which can control 3D rotation of single cells under different electric signal configurations. Electrical property measurement and 3D image reconstruction of single cells are achieved based on single-cell 3D rotation. This work overcomes the limitations of 2D planar electrodes and effectively solves the problem of unstable spatial position of single-cell samples, and provides a new platform for single-cell analysis. Based on multi-electrode structure of thick-electrode DEP, a microfluidic chip with optoelectronic integration was presented. A dual-fiber optical stretcher embedded in thick electrodes can trap and stretch a single cell while the thick electrodes are used for single-cell rotation. Stretching and rotation manipulation gives the chip the ability to simultaneously measure mechanical and electrical properties of single cells, providing a versatile platform for single-cell analysis, further extending the application of thick-electrode DEP in biological manipulation and analysis. |
| 700 1# - AUTHOR 2 | |
| Author 2 | Huang, Liang. |
| 700 1# - AUTHOR 2 | |
| Author 2 | Wang, Wenhui. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | https://doi.org/10.1007/978-3-031-01666-0 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | eBooks |
| 264 #1 - | |
| -- | Cham : |
| -- | Springer International Publishing : |
| -- | Imprint: Springer, |
| -- | 2020. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Engineering. |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biophysics. |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biomedical engineering. |
| 650 14 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Technology and Engineering. |
| 650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biophysics. |
| 650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biomedical Engineering and Bioengineering. |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| -- | 1930-0336 |
| 912 ## - | |
| -- | ZDB-2-SXSC |
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