Central Nervous System Tissue Engineering (Record no. 86080)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04411nam a22005535i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-3-031-02582-2 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240730165052.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220601s2012 sz | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| ISBN | 9783031025822 |
| -- | 978-3-031-02582-2 |
| 082 04 - CLASSIFICATION NUMBER | |
| Call Number | 571.4 |
| 100 1# - AUTHOR NAME | |
| Author | Wilkinson, Ashley E. |
| 245 10 - TITLE STATEMENT | |
| Title | Central Nervous System Tissue Engineering |
| Sub Title | Current Considerations and Strategies / |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. 2012. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Number of Pages | VIII, 112 p. |
| 490 1# - SERIES STATEMENT | |
| Series statement | Synthesis Lectures on Tissue Engineering, |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Remark 2 | Introduction -- Anatomy of the CNS and Progression of Neurological Damage -- Biomaterials for Scaffold Preparation -- Cell Sources for CNS TE -- Stimulation and Guidance -- Concluding Remarks. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Combating neural degeneration from injury or disease is extremely difficult in the brain and spinal cord, i.e. central nervous system (CNS). Unlike the peripheral nerves, CNS neurons are bombarded by physical and chemical restrictions that prevent proper healing and restoration of function. The CNS is vital to bodily function, and loss of any part of it can severely and permanently alter a person's quality of life. Tissue engineering could offer much needed solutions to regenerate or replace damaged CNS tissue. This review will discuss current CNS tissue engineering approaches integrating scaffolds, cells and stimulation techniques. Hydrogels are commonly used CNS tissue engineering scaffolds to stimulate and enhance regeneration, but fiber meshes and other porous structures show specific utility depending on application. CNS relevant cell sources have focused on implantation of exogenous cells or stimulation of endogenous populations. Somatic cells of the CNS are rarely utilized for tissue engineering; however, glial cells of the peripheral nervous system (PNS) may be used to myelinate and protect spinal cord damage. Pluripotent and multipotent stem cells offer alternative cell sources due to continuing advancements in identification and differentiation of these cells. Finally, physical, chemical, and electrical guidance cues are extremely important to neural cells, serving important roles in development and adulthood. These guidance cues are being integrated into tissue engineering approaches. Of particular interest is the inclusion of cues to guide stem cells to differentiate into CNS cell types, as well to guide neuron targeting. This review should provide the reader with a broad understanding of CNS tissue engineering challenges and tactics, with the goal of fostering the future development of biologically inspired designs. Table of Contents: Introduction / Anatomy of the CNS and Progression of Neurological Damage / Biomaterials for Scaffold Preparation / Cell Sources for CNS TE / Stimulation and Guidance / Concluding Remarks. |
| 700 1# - AUTHOR 2 | |
| Author 2 | McCormick, Aleesha M. |
| 700 1# - AUTHOR 2 | |
| Author 2 | Leipzig, Nic D. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | https://doi.org/10.1007/978-3-031-02582-2 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | eBooks |
| 264 #1 - | |
| -- | Cham : |
| -- | Springer International Publishing : |
| -- | Imprint: Springer, |
| -- | 2012. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biophysics. |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Materials science. |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Materials. |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biomedical engineering. |
| 650 14 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biophysics. |
| 650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Materials Science. |
| 650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Materials Engineering. |
| 650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biomedical Engineering and Bioengineering. |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| -- | 1944-0308 |
| 912 ## - | |
| -- | ZDB-2-SXSC |
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