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Data management of protein interaction networks / Mario Cannataro, Pietro Hiram Guzzi.

By: Cannataro, Mario, 1964-.
Contributor(s): Guzzi, Pietro Hiram, 1980- | IEEE Xplore (Online Service) [distributor.] | Wiley InterScience (Online service) [publisher.].
Material type: materialTypeLabelBookSeries: Wiley series in bioinformatics: 17Publisher: Hoboken, [New Jersey] : Wiley, [2012]Distributor: [Piscataqay, New Jersey] : IEEE Xplore, [2012]Description: 1 PDF (xxxiv, 182 pages) : illustrations (some color).Content type: text Media type: electronic Carrier type: online resourceISBN: 9781118103746.Subject(s): Protein-protein interactions -- Information resources | Information resources managementGenre/Form: Electronic books.Additional physical formats: Print version:: No titleDDC classification: 025.06/572644 Online resources: Abstract with links to resource Also available in print.
Contents:
Frontmatter -- Color Plates -- Interactomics -- Technologies for Discovering Protein Interactions -- Graph Theory and Applications -- Protein-To-Protein Interaction Data -- Protein-To-Protein Interaction DATABASES -- Models for Protein Interaction Networks -- Algorithms Analyzing Features of Protein Interaction Networks -- Algorithms Comparing Protein Interaction Networks -- Ontology-Based Analysis of Protein Interaction Networks -- Visualization of Protein Interaction Networks -- Case Studies in Biology and Bioinformatics -- Future Trends -- References -- Index.
Summary: "Current PPI databases do not offer sophisticated querying interfaces and especially do not integrate existing information about proteins. Current algorithms for PIN analysis use only topological information, while emerging approaches attempt to exploit the biological knowledge related to proteins and kinds of interaction, e.g. protein function, localization, structure, described in Gene Ontology or PDB. The book discusses technologies, standards and databases for, respectively, generating, representing and storing PPI data. It also describes main algorithms and tools for the analysis, comparison and knowledge extraction from PINs. Moreover, some case studies and applications of PINs are also discussed"-- Provided by publisher.
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Includes bibliographical references and index.

Frontmatter -- Color Plates -- Interactomics -- Technologies for Discovering Protein Interactions -- Graph Theory and Applications -- Protein-To-Protein Interaction Data -- Protein-To-Protein Interaction DATABASES -- Models for Protein Interaction Networks -- Algorithms Analyzing Features of Protein Interaction Networks -- Algorithms Comparing Protein Interaction Networks -- Ontology-Based Analysis of Protein Interaction Networks -- Visualization of Protein Interaction Networks -- Case Studies in Biology and Bioinformatics -- Future Trends -- References -- Index.

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"Current PPI databases do not offer sophisticated querying interfaces and especially do not integrate existing information about proteins. Current algorithms for PIN analysis use only topological information, while emerging approaches attempt to exploit the biological knowledge related to proteins and kinds of interaction, e.g. protein function, localization, structure, described in Gene Ontology or PDB. The book discusses technologies, standards and databases for, respectively, generating, representing and storing PPI data. It also describes main algorithms and tools for the analysis, comparison and knowledge extraction from PINs. Moreover, some case studies and applications of PINs are also discussed"-- Provided by publisher.

Also available in print.

Mode of access: World Wide Web

Description based on PDF viewed 12/22/2015.

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