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Title Page; Copyright; Dedication; Table of Contents; Preface; About the Companion Website; Chapter 1: An Overview of Bioprocess Technology and Biochemical Engineering; 1.1 A Brief History of Biotechnology and Biochemical Engineering; 1.2 Industrial Organisms; 1.3 Biotechnological Products; 1.4 Technology Life Cycle, and Genomics- and Stem Cell-Based New Biotechnology; Further Reading; Problems; Chapter 2: An Introduction to Industrial Microbiology and Cell Biotechnology; 2.1 Universal Features of Cells; 2.2 Cell Membranes, Barriers, and Transporters; 2.3 Energy Sources for Cells.

2.4 Material and Informational Foundation of Living Systems2.5 Cells of Industrial Importance; 2.6 Cells Derived from Multicellular Organisms; 2.7 Concluding Remarks; Further Reading; Problems; Chapter 3: Stoichiometry of Biochemical Reactions and Cell Growth; 3.1 Stoichiometry of Biochemical Reactions; 3.2 Stoichiometry for Cell Growth; 3.3 Hypothetical Partition of a Substrate for Biomass and Product Formation; 3.4 Metabolic Flux Analysis; 3.5 Concluding Remarks; Further Reading; Nomenclature; Problems; Chapter 4: Kinetics of Biochemical Reactions; 4.1 Enzymes and Biochemical Reactions.

4.2 Mechanics of Enzyme Reactions4.3 Michaelis-Menten Kinetics; 4.4 Determining the Value of Kinetic Parameters; 4.5 Other Kinetic Expressions; 4.6 Inhibition of Enzymatic Reactions; 4.7 Biochemical Pathways; 4.8 Reaction Network; 4.9 Regulation of Reaction Rates; 4.10 Transport across Membrane and Transporters; 4.11 Kinetics of Binding Reactions; 4.12 Concluding Remarks; Further Reading; Nomenclature; Problems; Chapter 5: Kinetics of Cell Growth Processes; 5.1 Cell Growth and Growth Kinetics; 5.2 Population Distribution; 5.3 Description of Growth Rate; 5.4 Growth Stage in a Culture.

5.5 Quantitative Description of Growth Kinetics5.6 Optimal Growth; 5.7 Product Formation; 5.8 Anchorage-Dependent Vertebrate Cell Growth; 5.9 Other Types of Growth Kinetics; 5.10 Kinetic Characterization of Biochemical Processes; 5.11 Applications of a Growth Model; 5.12 The Physiological State of Cells; 5.13 Kinetics of Cell Death; 5.14 Cell Death and the Sterilization of Medium; 5.15 Concluding Remarks; Further Reading; Nomenclature; Problems; Chapter 6: Kinetics of Continuous Culture; 6.1 Introduction; 6.2 Kinetic Description of a Continuous Culture.

6.3 Continuous Culture with Cell Recycling6.4 Specialty Continuous Cultures; 6.5 Transient Response of a Continuous Culture; 6.6 Concluding Remarks; Further Reading; Nomenclature; Problems; Chapter 7: Bioreactor Kinetics; 7.1 Bioreactors; 7.2 Basic Types of Bioreactors; 7.3 Comparison of CSTR and PFR; 7.4 Operating Mode of Bioreactors; 7.5 Configuration of Bioreactors; 7.6 Other Bioreactor Applications; 7.7 Cellular Processes through the Prism of Bioreactor Analysis; 7.8 Concluding Remarks; Further Reading; Nomenclature; Problems; Chapter 8: Oxygen Transfer in Bioreactors; 8.1 Introduction.

8.2 Oxygen Supply to Biological Systems.

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