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Mysteries in Muscle Contraction : Evidence Against Current Dogmas / Haruo Sugi.

By: Sugi, Haruo [author.].
Material type: materialTypeLabelBookPublisher: Singapore : Pan Stanford Publishing, [2018]Copyright date: ©2018Description: 1 online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9781315101910; 9781351590471.Subject(s): Muscle contractionAdditional physical formats: Print version: : No titleDDC classification: 612.74 Online resources: Click here to view.
Contents:
chapter 1 Historical Backgrouna -- chapter 2 Dogmas of Huxley-Simmons Model Not Supported Experimentally -- chapter 3 New Methods and New Dogmas and Their Shortcomings 27 3.1 The Lymn-Taylor Scheme of Actomyosin ATPase Reaction -- chapter 4 The Swinging Lever Arm Mechanism: A Most Prominent Current Dogma -- chapter 5 Early Electron Microscopic Studies on Myosin Head Movement Using Quick-freeze, Deep-Etch Replica Method -- chapter 6 Electron Microscopic Recording of ATP-Induced Myosin Head Movement Using the Gas Environmental Chamber -- chapter 7 Evidence against Current Dogmas and Mechanism of Muscle Contraction as Revealed by the Effect of Antibodies on Myosin Head -- chapter 8 Electron Microscopic Recording of Myosin Head Power Stroke: Evidence That Myosin Heads Take the Neutral Position When Detached from Actin Filaments -- chapter 9 The Fenn Effect: A Fundamental Mystery in Muscle -- chapter 10 Load-Dependent Mechanical Efficiency of Myosin Head Performance -- chapter 11 Past History-Dependence of Myosin Head Performance -- chapter 12 Reminiscences of My Early Work: I. Summation of Force Responses in Muscle -- chapter 13 Reminiscences of My Early Work: II. Transverse Spread Contraction Initiated by Local Membrane Depolarization in Single Muscle Fibers -- chapter 14 Epilogue.
Summary: "The book explores author's wide-ranging work on muscle research for more than 50 years. It delves into the dogmas of muscle contraction, how the models were constructed and what was overlooked during the process, including their resulting shortcomings. In all chapters, the author intends to stimulate interest of general readers and specific researchers which also highlights the author's pioneering work on the electron microscopic recording of myosin head power and recovery strokes, including a frank discussion on how the original work sometimes tends to be overlooked by competing scientists, who hinder the progress of science."--Provided by publisher.
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chapter 1 Historical Backgrouna -- chapter 2 Dogmas of Huxley-Simmons Model Not Supported Experimentally -- chapter 3 New Methods and New Dogmas and Their Shortcomings 27 3.1 The Lymn-Taylor Scheme of Actomyosin ATPase Reaction -- chapter 4 The Swinging Lever Arm Mechanism: A Most Prominent Current Dogma -- chapter 5 Early Electron Microscopic Studies on Myosin Head Movement Using Quick-freeze, Deep-Etch Replica Method -- chapter 6 Electron Microscopic Recording of ATP-Induced Myosin Head Movement Using the Gas Environmental Chamber -- chapter 7 Evidence against Current Dogmas and Mechanism of Muscle Contraction as Revealed by the Effect of Antibodies on Myosin Head -- chapter 8 Electron Microscopic Recording of Myosin Head Power Stroke: Evidence That Myosin Heads Take the Neutral Position When Detached from Actin Filaments -- chapter 9 The Fenn Effect: A Fundamental Mystery in Muscle -- chapter 10 Load-Dependent Mechanical Efficiency of Myosin Head Performance -- chapter 11 Past History-Dependence of Myosin Head Performance -- chapter 12 Reminiscences of My Early Work: I. Summation of Force Responses in Muscle -- chapter 13 Reminiscences of My Early Work: II. Transverse Spread Contraction Initiated by Local Membrane Depolarization in Single Muscle Fibers -- chapter 14 Epilogue.

"The book explores author's wide-ranging work on muscle research for more than 50 years. It delves into the dogmas of muscle contraction, how the models were constructed and what was overlooked during the process, including their resulting shortcomings. In all chapters, the author intends to stimulate interest of general readers and specific researchers which also highlights the author's pioneering work on the electron microscopic recording of myosin head power and recovery strokes, including a frank discussion on how the original work sometimes tends to be overlooked by competing scientists, who hinder the progress of science."--Provided by publisher.

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