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Functional proteomics / Luke Erber, Yue Chen.

By: Erber, Luke [author.].
Contributor(s): Chen, Yue. University of Minnesota College of Biological Sciences [author.] | American Chemical Society.
Material type: materialTypeLabelBookSeries: ACS in focus: Publisher: [Washington, DC] : American Chemical Society, [2021]Description: 1 online resource : illustrations (some color).Content type: text Media type: computer Carrier type: online resourceISBN: 9780841299245.Subject(s): Proteomics | ProteinsDDC classification: 572.6 Online resources: Click here to access online
Contents:
Fundamentals of Mass Spectrometry-Based Protein Identification and Quantification -- Interaction Proteomics: Defining the Cellular Interaction Network -- Activity-Based Proteomic Analysis: Defining Chemical and Enzymatic Targeted Proteome -- Structural Proteomic Analysis: Defining Structural Functional Relationship in Proteome -- Proteomic Analysis of Post-Translational Modifications: Defining Functional Post-Translational Modification Isoforms in Cellular Processes -- Spatial Proteomic Analysis: Defining Organelle and Tissue Proteome -- Temporal Proteomic Analysis: Defining Temporal Dynamics of Cellular Proteome.
Summary: "The fundamental importance of proteins in cellular activity and drug discovery combined with the enormous complexity of proteoforms requires wide-ranging strategies to characterize the proteome at a system-wide scale. Because of its speed, sensitivity, and reliability, mass spectrometry–based proteomics technology has become a critical platform for systematic analysis of proteins. Functional Proteomics covers the basic knowledge about and summarizes some of the latest developments in this field as an introduction for anyone interested in applying functional proteomics strategies to study biological pathways and diseases."-- provided by publisher.
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Includes bibliographical references and index.

Fundamentals of Mass Spectrometry-Based Protein Identification and Quantification -- Interaction Proteomics: Defining the Cellular Interaction Network -- Activity-Based Proteomic Analysis: Defining Chemical and Enzymatic Targeted Proteome -- Structural Proteomic Analysis: Defining Structural Functional Relationship in Proteome -- Proteomic Analysis of Post-Translational Modifications: Defining Functional Post-Translational Modification Isoforms in Cellular Processes -- Spatial Proteomic Analysis: Defining Organelle and Tissue Proteome -- Temporal Proteomic Analysis: Defining Temporal Dynamics of Cellular Proteome.

"The fundamental importance of proteins in cellular activity and drug discovery combined with the enormous complexity of proteoforms requires wide-ranging strategies to characterize the proteome at a system-wide scale. Because of its speed, sensitivity, and reliability, mass spectrometry–based proteomics technology has become a critical platform for systematic analysis of proteins. Functional Proteomics covers the basic knowledge about and summarizes some of the latest developments in this field as an introduction for anyone interested in applying functional proteomics strategies to study biological pathways and diseases."-- provided by publisher.

American Chemical Society, ACS In Focus eBooks - 2021 Front Files.

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