Education and Training -- Theory-based development of an inventory for the evaluation of simulation game lectures -- Exploring the use of immersive virtual reality games in a formal school environment -- Learning effects and acceptance in business games: A systematic literature review -- About dinosaurs in laboratories - Evaluation of the serious game Cards for Biosafety -- Design consideration of an educational video game through the lens of the metalanguage -- Resilience and Sustainability -- Quantitative analysis of conflict-of-interest structures in the consensus building process -- Feedback on a "territory-responsive" participatory simulation on coastal flooding risk applied to two case studies in France -- Simulation games on sustainability - A comparative study -- Stop work: Serious games as intervention method to enhance safety behavior -- Gaming simulation design to learn best mix of power sources -- Health -- Reducept VR: The importance of a design rationale for the immersiveness of a virtual reality game to support chronic pain treatment effectively -- How playfulness can enable greater understanding of game-based adult mental health interventions -- Measuring the interaction of conflict-minimizing and goal-seeking motor imperatives in autism spectrum disorder -- Resto Quest - A serious game on the restorative effects of immersive virtual environments -- Social Justice -- A moderated mediation analysis of meaningfulness and positive intergroup outcomes through game-based interactive storytelling.

This book constitutes revised selected papers from the 53rd International Simulation and Gaming Association Conference, ISAGA 2022, which took place in Boston, USA, during July 11-14, 2022. The 15 full papers presented in this volume were carefully reviewed and selected from 35 submissions. They were organized in topical sections named: education and training; resilience and sustainability; health; and social justice.