Multiscale Mechanobiology of Bone Remodeling and Adaptation  [electronic resource] / 
edited by Peter Pivonka. 
 - 1st ed. 2018. 
 - XII, 287 p. 98 illus.  online resource. 
 - CISM International Centre for Mechanical Sciences, Courses and Lectures,  578  2309-3706 ; .
 - CISM International Centre for Mechanical Sciences, Courses and Lectures,  578 .
<br/><br/>Bone cell biology and mechanobiology -- Disease systems analysis of osteoporosis and treatments -- Bone quality assessment across the scales -- Interaction of bone tissue with other tissues including muscle, cartilage, and vascularization -- Musculoskeletal modeling of human movement -- Image-based 3D micro-FE modeling. 
<br/><br/> The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations. 
<br/><br/><label>ISBN: </label>9783319588452 
<br/><br/><label>Standard No.: </label>10.1007/978-3-319-58845-2  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Mechanics, Applied.<br/>Solids.<br/>Biomaterials.<br/>Orthopedics.<br/>Solid Mechanics.<br/>Biomaterials.<br/>Orthopaedics.
<br/><br/><label>LC Class. No.: </label>TA349-359 
<br/><br/><label>Dewey Class. No.: </label>620.105