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Multicomponent reactions : synthesis of bioactive heterocycles / [edited by] K.L. Ameta and Anshu Dandia.

Contributor(s): Ameta, K. L | Dandia, Anshu.
Material type: materialTypeLabelBookPublisher: Boca Raton : CRC Press, 2017Description: 1 online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9781315333687; 9781315369754.Subject(s): Bioactive compounds | Heterocyclic compounds -- Synthesis | Heterocyclic compounds | Heterogeneous catalysisAdditional physical formats: Print version: : No titleDDC classification: 547.59 Online resources: Click here to view.
Contents:
chapter 1 Synthesis of Pyridines by Multicomponent Reactions / Giammarco Tenti M. Teresa Ramos J. Carlos Menéndez -- chapter 2 Isocyanide-Based Multicomponent Reactions Based upon Intramolecular Nitrilium Trapping / Susruta Majumdar András Váradi Travis C. Palmer -- chapter 3 The Role of Nanoporous Materials in Multicomponent Synthesis/Modification of Heterocyclic Compounds / Esmail Doustkhah Sadegh Rostamnia -- chapter 4 Multicomponent Reactions of Amino Acids and Their Derivatives in Heterocycle Chemistry / Nahid S. Alavijeh Somayeh Ahadi Saeed Balalaie -- chapter 5 Multicomponent Reactions for Generation of Molecular Libraries in Anticancer Drug Discovery / Mohammad Saquib Mohammad Faheem Khan Mohammad Imran Ansari Irfan Khan Mohammad Kamil Hussain Jagdamba Singh -- chapter 6 Transition Metal Catalyzed Synthesis of Heterocycles via Multicomponent Reactions / Satavisha Sarkar Arghya Banerjee Bhisma K. Patel -- chapter 7 Synthesis of Fluorinated Heterocycles via Multicomponent Reactions / Sandip S. Shinde S. N. Thore Rajendra P. Pawar K. L. Ameta Sunil N. Patil -- chapter 8 One-Pot Total Synthesis of Bioactive Natural Products / Jiachen Xiang Miao Wang Yu Sun Anxin Wu -- chapter 9 Modern Synthesis of Bioactive Heterocycles via IMCR Modification / Anshu Dandia Shahnawaz Khan Vijay Parewa Amit Sharma Begraj Kumawat -- chapter 10 Recent Progress on One-Pot, Multicomponent Reaction for Pyridine Synthesis / Vijaykumar Paike Padmakar Suryavanshi Sandeep More Sandeep B. Mane Rajendra P. Pawar K. L. Ameta -- chapter 11 Synthesis of Functionalized Piperidine Derivatives Based on Multicomponent Reaction / Padmakar Suryavanshi Vijaykumar Paike Sandeep More Rajendra P. Pawar Sandeep B. Mane K. L. Ameta -- chapter 12 Malononitrile: A Key Reagent for the Synthesis of Medicinally Promising Fused and Spiro Pyridine Derivatives in Multicomponent Reactions / Ruby Singh K. L. Ameta -- chapter 13 Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones/Thiones and Polyhydroquinolines via Multicomponent Reactions / Thomas J. Laughlin Joshua S. Yoo Ram S. Mohan.
Summary: "This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential."--Provided by publisher.
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chapter 1 Synthesis of Pyridines by Multicomponent Reactions / Giammarco Tenti M. Teresa Ramos J. Carlos Menéndez -- chapter 2 Isocyanide-Based Multicomponent Reactions Based upon Intramolecular Nitrilium Trapping / Susruta Majumdar András Váradi Travis C. Palmer -- chapter 3 The Role of Nanoporous Materials in Multicomponent Synthesis/Modification of Heterocyclic Compounds / Esmail Doustkhah Sadegh Rostamnia -- chapter 4 Multicomponent Reactions of Amino Acids and Their Derivatives in Heterocycle Chemistry / Nahid S. Alavijeh Somayeh Ahadi Saeed Balalaie -- chapter 5 Multicomponent Reactions for Generation of Molecular Libraries in Anticancer Drug Discovery / Mohammad Saquib Mohammad Faheem Khan Mohammad Imran Ansari Irfan Khan Mohammad Kamil Hussain Jagdamba Singh -- chapter 6 Transition Metal Catalyzed Synthesis of Heterocycles via Multicomponent Reactions / Satavisha Sarkar Arghya Banerjee Bhisma K. Patel -- chapter 7 Synthesis of Fluorinated Heterocycles via Multicomponent Reactions / Sandip S. Shinde S. N. Thore Rajendra P. Pawar K. L. Ameta Sunil N. Patil -- chapter 8 One-Pot Total Synthesis of Bioactive Natural Products / Jiachen Xiang Miao Wang Yu Sun Anxin Wu -- chapter 9 Modern Synthesis of Bioactive Heterocycles via IMCR Modification / Anshu Dandia Shahnawaz Khan Vijay Parewa Amit Sharma Begraj Kumawat -- chapter 10 Recent Progress on One-Pot, Multicomponent Reaction for Pyridine Synthesis / Vijaykumar Paike Padmakar Suryavanshi Sandeep More Sandeep B. Mane Rajendra P. Pawar K. L. Ameta -- chapter 11 Synthesis of Functionalized Piperidine Derivatives Based on Multicomponent Reaction / Padmakar Suryavanshi Vijaykumar Paike Sandeep More Rajendra P. Pawar Sandeep B. Mane K. L. Ameta -- chapter 12 Malononitrile: A Key Reagent for the Synthesis of Medicinally Promising Fused and Spiro Pyridine Derivatives in Multicomponent Reactions / Ruby Singh K. L. Ameta -- chapter 13 Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones/Thiones and Polyhydroquinolines via Multicomponent Reactions / Thomas J. Laughlin Joshua S. Yoo Ram S. Mohan.

"This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential."--Provided by publisher.

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