"A CRC title, part of the Taylor & Francis imprint, a member of the Taylor & Francis Group, the academic division of T&F Informa plc."

Includes bibliographical references.

chapter 1 Introduction to 3D Test Systems / Karen J. L. Burg Didier Dréau Timothy Burg -- chapter 2 Biofabrication / Jordon Gilmore Timothy Burg -- chapter 3 Bioreactor Instrumentation and Control for 3D Cellular and Tissue Systems / Steve Warren -- chapter 4 Control of 3D EnvironmentRedesign of the Flow Loop Bioreactor to Control Mitral Valve Regurgitation / Patrick S. Connell Dragoslava P. Vekilov K. Jane Grande-Allen -- chapter 5 Nipple and Breast Construction: In Vitro and In Vivo Assessment / Maria Yanez Scott Collins Thomas Boland -- chapter 6 3D Cancer Spheroid Biofabrication Using Thermal Inkjet-Based Bioprinting for Rapid Screening / Jorge I. Rodríguez-Dévora Christopher Moody Aesha Desai Karen J. L. Burg Delphine Dean -- section I Biofabrication Considerations -- chapter 7 Control Testing and Effect of Manufacturing Parameters on the Biocompatibility of Polypropylene Mesh Implants / Ahmed El-Ghannam -- chapter 8 Scaffolds for 3D Model Systems in Bone Regenerative Engineering / Keshia Ashe Seth Malinowski Yusuf Khan Cato T. Laurencin -- chapter 9 Engineered Composites for 3D Mammary Tissue Systems / Cheryl T. Gomillion Chih-Chao Yang Didier Dréau Karen J. L. Burg -- chapter 10 Mineralized 3D Culture Systems for Studying Bone Metastatic Breast Cancer / Frank He Siyoung Choi Lara A. Estroff Claudia Fischbach -- chapter 11 Design Considerations for 3D Cardiovascular Tissue Scaffolds / Scott Cooper Christopher Moraes Richard L. Leask -- section II Materials Considerations -- chapter 12 Pro- and Anti-Inflammatory Cytokine Signaling within 3D Tissue Models / Stephen L. Rego Tian McCann Didier Dréau -- chapter 13 Cell-Cell Communications through Gap Junctions and Cancer in 3D Systems / Stephanie Nicole Shishido Thu Annelise Nguyen -- chapter 14 Advances in Breast Stem Cell Knowledge through 3D Systems / Kerri W. Kwist Brian W. Booth -- chapter 15 Shape Matters: Understanding the Breast through 3D Tissue Culture Models / Lucia Speroni Ana M. Soto Carlos Sonnenschein -- chapter 16 Cells and Tissue Structures in Cardiovascular 3D Tissue Systems / Justin McMahan Rachel Hybart C. LaShan Simpson -- chapter 17 Signaling and Architectural Cues Necessary for 3D Diabetic Tissue Models / Rosalyn D. Abbott David L. Kaplan -- chapter 18 Optimizing 3D Models of Engineered Skeletal Muscle / Megan E. Kondash Brittany N. J. Davis George A. Truskey -- chapter 19 Recapitulating the Microenvironment of Glioblastoma Multiforme Using 3D Tissue Culture Models / Meghan Logun Steven Stice Lohitash Karumbaiah -- section III Biological Considerations -- chapter 20 Bringing Regenerative Medicine to Patients: The Coverage, Coding, and Reimbursement Processes / Khin-Kyemon Aung Scott Levy Sujata K. Bhatia -- section IV Business Considerations.

"Engineering 3D Tissue Test Systems provides an introduction to, and unique coverage of, a rapidly evolving area in biomaterials engineering. It reveals the current and future research responses, the current and future diagnostic applications, and provides a comprehensive overview to foster innovation. It offers insight into the importance of 3D systems and their use as benchtop models, spanning applications from basic scientific research to clinical diagnostics. Methods and limitations of building 3D tissue structures are evaluated, with attention given to the cellular, polymeric, and fabrication instrumentation components. The book covers the important aspects of polymeric tissue test systems, highlighting the needs and constraints of the industry, and includes a chapter on regulatory and pricing issues."--Provided by publisher.