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Multiscale Mechanobiology of Bone Remodeling and Adaptation [electronic resource] / edited by Peter Pivonka.

Contributor(s): Pivonka, Peter [editor.] | SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: CISM International Centre for Mechanical Sciences, Courses and Lectures: 578Publisher: Cham : Springer International Publishing : Imprint: Springer, 2018Edition: 1st ed. 2018.Description: XII, 287 p. 98 illus. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9783319588452.Subject(s): Mechanics, Applied | Solids | Biomaterials | Orthopedics | Solid Mechanics | Biomaterials | OrthopaedicsAdditional physical formats: Printed edition:: No title; Printed edition:: No title; Printed edition:: No titleDDC classification: 620.105 Online resources: Click here to access online
Contents:
Bone cell biology and mechanobiology -- Disease systems analysis of osteoporosis and treatments -- Bone quality assessment across the scales -- Interaction of bone tissue with other tissues including muscle, cartilage, and vascularization -- Musculoskeletal modeling of human movement -- Image-based 3D micro-FE modeling.
In: Springer Nature eBookSummary: The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.
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Bone cell biology and mechanobiology -- Disease systems analysis of osteoporosis and treatments -- Bone quality assessment across the scales -- Interaction of bone tissue with other tissues including muscle, cartilage, and vascularization -- Musculoskeletal modeling of human movement -- Image-based 3D micro-FE modeling.

The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.

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