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001 978-3-642-54464-4
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005 20200420220219.0
007 cr nn 008mamaa
008 140422s2014 gw | s |||| 0|eng d
020 _a9783642544644
_9978-3-642-54464-4
024 7 _a10.1007/978-3-642-54464-4
_2doi
050 4 _aR856-857
072 7 _aMQW
_2bicssc
072 7 _aTEC009000
_2bisacsh
082 0 4 _a610.28
_223
245 1 0 _aData-driven Modeling for Diabetes
_h[electronic resource] :
_bDiagnosis and Treatment /
_cedited by Vasilis Marmarelis, Georgios Mitsis.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2014.
300 _aX, 237 p. 74 illus., 40 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aLecture Notes in Bioengineering,
_x2195-271X
505 0 _aHypoglycemia Prevention using Low Glucose Suspend Systems -- Linear Modeling and Prediction in Diabetes Physiology -- Adaptive Algorithms for Personalized Diabetes Treatment -- Data-driven modeling of Diabetes Progression -- Nonlinear Modeling of the Dynamic Effects of Free Fatty Acids on Insulin Sensitivity -- Data-driven and Mininal-type Compartmental Insulin-Glucose Models: Theory and Applications -- Pitfalls in model identification: examples from Glucose-Insulin modelling -- Ensemble Glucose Prediction in Insulin-Dependent Diabetes -- Simple parameters describing gut absorption and lipid dynamics in relation to glucose metabolism during a routine oral glucose test -- Simulation Models for In-Silico Evaluation of Closed-Loop Insulin Delivery Systems in Type 1 Diabetes.
520 _aThis contributed volume presents computational models of diabetes that quantify the dynamic interrelationships among key physiological variables implicated in the underlying physiology under a variety of metabolic and behavioral conditions. These variables comprise for example blood glucose concentration and various hormones such as insulin, glucagon, epinephrine, norepinephrine as well as cortisol. The presented models provide a powerful diagnostic tool but may also enable treatment via long-term glucose regulation in diabetics through closed-look model-reference control using frequent insulin infusions, which are administered by implanted programmable micro-pumps. This research volume aims at presenting state-of-the-art research on this subject and demonstrating the potential applications of modeling to the diagnosis and treatment of diabetes. The target audience primarily comprises research and experts in the field but the book may also be beneficial for graduate students.
650 0 _aEngineering.
650 0 _aHuman physiology.
650 0 _aDiabetes.
650 0 _aBiomathematics.
650 0 _aBiomedical engineering.
650 1 4 _aEngineering.
650 2 4 _aBiomedical Engineering.
650 2 4 _aDiabetes.
650 2 4 _aHuman Physiology.
650 2 4 _aPhysiological, Cellular and Medical Topics.
700 1 _aMarmarelis, Vasilis.
_eeditor.
700 1 _aMitsis, Georgios.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642544637
830 0 _aLecture Notes in Bioengineering,
_x2195-271X
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-54464-4
912 _aZDB-2-ENG
942 _cEBK
999 _c51781
_d51781