000 | 04930nam a22006015i 4500 | ||
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001 | 978-3-642-40193-0 | ||
003 | DE-He213 | ||
005 | 20200421111203.0 | ||
007 | cr nn 008mamaa | ||
008 | 131223s2014 gw | s |||| 0|eng d | ||
020 |
_a9783642401930 _9978-3-642-40193-0 |
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024 | 7 |
_a10.1007/978-3-642-40193-0 _2doi |
|
050 | 4 | _aQA75.5-76.95 | |
072 | 7 |
_aUY _2bicssc |
|
072 | 7 |
_aUYA _2bicssc |
|
072 | 7 |
_aCOM014000 _2bisacsh |
|
072 | 7 |
_aCOM031000 _2bisacsh |
|
082 | 0 | 4 |
_a004.0151 _223 |
245 | 1 | 0 |
_aDiscrete and Topological Models in Molecular Biology _h[electronic resource] / _cedited by Nataša Jonoska, Masahico Saito. |
264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2014. |
|
300 |
_aXIII, 524 p. 211 illus., 154 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
||
490 | 1 |
_aNatural Computing Series, _x1619-7127 |
|
505 | 0 | _aChap. 1 - Perspectives in Computational Genome Analysis -- Chap. 2 - The Sequence Reconstruction Problem -- Chap. 3 - Extracting Coevolving Characters from a Tree of Species -- Chap. 4 - When and How the Perfect Phylogeny Model Explains Evolution -- Chap. 5 - An Invitation to the Study of Brain Networks with Some Statistical Analysis of Thresholding Techniques -- Chap. 6 - Simplicial Models and Topological Inference in Biological Systems -- Chap. 7 - Combinatorial Insights into RNA Secondary Structure -- Chap. 8 - Redundant and Critical Noncovalent Interactions in Protein Rigid Cluster Analysis -- Chap. 9 - Modeling Autonomous Supramolecular Assembly -- Chap. 10 - The Role of Symmetry in Conformational Changes of Viral Capsids: A Mathematical Approach -- Chap. 11 - Minimal Tile and Bond-Edge Types for Self-Assembling DNA Graphs -- Chap. 12 - Programmed Genome Processing in Ciliates -- Chap. 13 - The Algebra of Gene Assembly in Ciliates -- Chap. 14 - Invariants of Graphs Modeling Nucleotide Rearrangements -- Chap. 15 - Introduction to DNA Topology -- Chap. 16 - Reactions Mediated by Topoisomerases and Other Enzymes: Modelling Localised DNA Transformations -- Chap. 17 - Site-Specific Recombination on Unknot and Unlink Substrates Producing Two-Bridge Links -- Chap. 18 - Site-Specific Recombination Modeled as a Band Surgery: Applications to Xer Recombination -- Chap. 19 - Understanding DNA Looping Through Cre-Recombination Kinetics -- Chap. 20 - The QSSA in Chemical Kinetics: As taught and as Practiced -- Chap. 21 - Algebraic Models and Their Use in Systems Biology -- Chap. 22 - Deconstructing Complex Nonlinear Models in System Design Space -- Chap. 23 - IBCell Morphocharts: A Computational Model for Linking Cell Molecular Activity with Emerging Tissue Morphology. | |
520 | _aTheoretical tools and insights from discrete mathematics, theoretical computer science, and topology now play essential roles in our understanding of vital biomolecular processes. The related methods are now employed in various fields of mathematical biology as instruments to "zoom in" on processes at a molecular level. This book contains expository chapters on how contemporary models from discrete mathematics - in domains such as algebra, combinatorics, and graph and knot theories - can provide perspective on biomolecular problems ranging from data analysis, molecular and gene arrangements and structures, and knotted DNA embeddings via spatial graph models to the dynamics and kinetics of molecular interactions. The contributing authors are among the leading scientists in this field and the book is a reference for researchers in mathematics and theoretical computer science who are engaged with modeling molecular and biological phenomena using discrete methods. It may also serve as a guide and supplement for graduate courses in mathematical biology or bioinformatics, introducing nontraditional aspects of mathematical biology. | ||
650 | 0 | _aComputer science. | |
650 | 0 | _aComputers. | |
650 | 0 | _aSystems biology. | |
650 | 0 | _aCell biology. | |
650 | 0 | _aEvolutionary biology. | |
650 | 0 | _aBiomathematics. | |
650 | 0 | _aBiological systems. | |
650 | 1 | 4 | _aComputer Science. |
650 | 2 | 4 | _aTheory of Computation. |
650 | 2 | 4 | _aMathematical and Computational Biology. |
650 | 2 | 4 | _aEvolutionary Biology. |
650 | 2 | 4 | _aSystems Biology. |
650 | 2 | 4 | _aCell Biology. |
650 | 2 | 4 | _aBiological Networks, Systems Biology. |
700 | 1 |
_aJonoska, Nataša. _eeditor. |
|
700 | 1 |
_aSaito, Masahico. _eeditor. |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783642401923 |
830 | 0 |
_aNatural Computing Series, _x1619-7127 |
|
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-642-40193-0 |
912 | _aZDB-2-SCS | ||
942 | _cEBK | ||
999 |
_c53935 _d53935 |