000			03158nam a22005055i 4500
001			978-1-4939-1865-2
003			DE-He213
005			20200421111836.0
007			cr nn 008mamaa
008			141121s2015 xxu| s |||| 0|eng d
020			_a9781493918652 _9978-1-4939-1865-2
024	7		_a10.1007/978-1-4939-1865-2 _2doi
050		4	_aR856-857
072		7	_aMQW _2bicssc
072		7	_aTEC009000 _2bisacsh
082	0	4	_a610.28 _223
100	1		_aYannas, Ioannis V. _eauthor.
245	1	0	_aTissue and Organ Regeneration in Adults _h[electronic resource] : _bExtension of the Paradigm to Several Organs / _cby Ioannis V. Yannas.
250			_a2nd ed. 2015.
264		1	_aNew York, NY : _bSpringer New York : _bImprint: Springer, _c2015.
300			_aXXIII, 332 p. 61 illus., 21 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aThe Irreversibility of Organ Injury -- Nonregenerative Tissues -- Experimental Methods I. The Anatomically Well-Defined Wound -- Experimental Methods II. The Defect Closure Rule -- Regeneration of Skin -- Regeneration of a Peripheral Nerve -- Minimum Reactants Required for Synthesis of Skin and Peripheral Nerves; Extension to Tissues of Other  Organs -- An Antagonistic Relation Between Wound Contraction and Regeneration -- Molecular biology of contraction blockade by active scaffolds -- The Scaffold Regeneration Paradigm and its Consequences.
520			_aThis textbook describes the basic principles of induced organ regeneration in skin and peripheral nerves and extends the original successful paradigm to other organs. A set of trans-organ rules is established and its use in regeneration of several organs is illustrated from the works of several independent investigators who worked with a variety of organs, such as the lung, the bladder, and the Achilles tendon, using collagen-based scaffolds somewhat similar to the original one. These critical medical treatments fill the clinical need that is not met by organ transplantation. New to this second edition: New information extending the paradigm of tissue regeneration from organ regeneration in skin and peripheral nerves to other organs Guidelines, known as trans-organ rules, are described for the first time for extending this unique medical treatment to organs of several medical specialties The work serves as a comprehensive text and reference for students and practitioners of tissue engineering  .
650		0	_aEngineering.
650		0	_aBiotechnology.
650		0	_aDermatology.
650		0	_aBiomedical engineering.
650		0	_aBiomaterials.
650	1	4	_aEngineering.
650	2	4	_aBiomedical Engineering.
650	2	4	_aBiomaterials.
650	2	4	_aDermatology.
650	2	4	_aBiotechnology.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781493918645
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4939-1865-2
912			_aZDB-2-ENG
942			_cEBK
999			_c55279 _d55279