000			03735nam a22005415i 4500
001			978-3-642-28554-7
003			DE-He213
005			20200421111849.0
007			cr nn 008mamaa
008			130717s2014 gw | s |||| 0|eng d
020			_a9783642285547 _9978-3-642-28554-7
024	7		_a10.1007/978-3-642-28554-7 _2doi
050		4	_aQ342
072		7	_aUYQ _2bicssc
072		7	_aCOM004000 _2bisacsh
082	0	4	_a006.3 _223
245	1	0	_aComputational Methods to Study the Structure and Dynamics of Biomolecules and Biomolecular Processes _h[electronic resource] : _bFrom Bioinformatics to Molecular Quantum Mechanics / _cedited by Adam Liwo.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2014.
300			_aXIV, 810 p. 210 illus., 90 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aSpringer Series in Bio-/Neuroinformatics, _x2193-9349 ; _v1
505	0		_aMolecular simulations: methodology -- Molecular simulations: applications -- Use of structural database or experimental information in modeling protein structure and dynamics -- Applications of molecular quantum mechanics.
520			_aSince the second half of the 20th century machine computations have played a critical role in science and engineering. Computer-based techniques have become especially important in molecular biology, since they often represent the only viable way to gain insights into the behavior of a biological system as a whole. The complexity of biological systems, which usually needs to be analyzed on different time- and size-scales and with different levels of accuracy, requires the application of different approaches, ranging from comparative analysis of sequences and structural databases, to the analysis of networks of interdependence between cell components and processes, through coarse-grained modeling to atomically detailed simulations, and finally to molecular quantum mechanics. This book provides a comprehensive overview of modern computer-based techniques for computing the structure, properties and dynamics of biomolecules and biomolecular processes. The twenty-two chapters, written by scientists from all over the world, address the theory and practice of computer simulation techniques in the study of biological phenomena. The chapters are grouped into four thematic sections dealing with the following topics: the methodology of molecular simulations; applications of molecular simulations; bioinformatics methods and use of experimental information in molecular simulations; and selected applications of molecular quantum mechanics. The book includes an introductory chapter written by Harold A. Scheraga, one of the true pioneers in simulation studies of biomacromolecules.
650		0	_aEngineering.
650		0	_aChemistry, Physical and theoretical.
650		0	_aBioinformatics.
650		0	_aProteins.
650		0	_aMechanics.
650		0	_aComputational intelligence.
650	1	4	_aEngineering.
650	2	4	_aComputational Intelligence.
650	2	4	_aComputational Biology/Bioinformatics.
650	2	4	_aProtein Science.
650	2	4	_aTheoretical and Computational Chemistry.
650	2	4	_aMechanics.
700	1		_aLiwo, Adam. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783642285530
830		0	_aSpringer Series in Bio-/Neuroinformatics, _x2193-9349 ; _v1
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-642-28554-7
912			_aZDB-2-ENG
942			_cEBK
999			_c56000 _d56000