| 000 | 03036nam a22005415i 4500 | ||
|---|---|---|---|
| 001 | 978-3-319-30237-9 | ||
| 003 | DE-He213 | ||
| 005 | 20200421112223.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 160301s2016 gw | s |||| 0|eng d | ||
| 020 |
_a9783319302379 _9978-3-319-30237-9 |
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| 024 | 7 |
_a10.1007/978-3-319-30237-9 _2doi |
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| 050 | 4 | _aR856-857 | |
| 072 | 7 |
_aMQW _2bicssc |
|
| 072 | 7 |
_aTEC009000 _2bisacsh |
|
| 082 | 0 | 4 |
_a610.28 _223 |
| 100 | 1 |
_aFrega, Monica. _eauthor. |
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| 245 | 1 | 0 |
_aNeuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems _h[electronic resource] / _cby Monica Frega. |
| 250 | _a1st ed. 2016. | ||
| 264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2016. |
|
| 300 |
_aXIII, 148 p. 97 illus., 43 illus. in color. _bonline resource. |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
||
| 490 | 1 |
_aSpringer Theses, Recognizing Outstanding Ph.D. Research, _x2190-5053 |
|
| 505 | 0 | _aIntroduction -- Dissociated Neuronal Networks Coupled to Micro-Electrode Arrays Devices -- In Vitro Neuronal Networks -- 3D Neuronal Networks: State of the Art -- 3D Neuronal Networks Coupled to MEAs -- Neuro-pharmacological Studies -- Discussion and Conclusion -- Data Analysis. | |
| 520 | _aThe book presents a new, powerful model of neuronal networks, consisting of a three-dimensional neuronal culture in which 3D neuronal networks are coupled to micro-electrode-arrays (MEAs). It discusses the main advantages of the three-dimensional system compared to its two-dimensional counterpart, and shows that the network dynamics, recorded during both spontaneous and stimulated activity, differs between the two models, with the 3D system being better able to emulate the in vivo behaviour of neural networks. The book offers an extensive analysis of the system, from the theoretical background, to its design and applications in neuro-pharmacological studies. Moreover, it includes a concise yet comprehensive introduction to both 2D and 3D neuronal networks coupled to MEAs, and discusses the advantages, limitations and challenges of their applications as cellular and tissue-like in vitro experimental model systems. < . | ||
| 650 | 0 | _aEngineering. | |
| 650 | 0 | _aNeurosciences. | |
| 650 | 0 | _aCell physiology. | |
| 650 | 0 | _aElectronics. | |
| 650 | 0 | _aMicroelectronics. | |
| 650 | 0 | _aBiomedical engineering. | |
| 650 | 1 | 4 | _aEngineering. |
| 650 | 2 | 4 | _aBiomedical Engineering. |
| 650 | 2 | 4 | _aCell Physiology. |
| 650 | 2 | 4 | _aElectronics and Microelectronics, Instrumentation. |
| 650 | 2 | 4 | _aNeurosciences. |
| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9783319302362 |
| 830 | 0 |
_aSpringer Theses, Recognizing Outstanding Ph.D. Research, _x2190-5053 |
|
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-319-30237-9 |
| 912 | _aZDB-2-ENG | ||
| 942 | _cEBK | ||
| 999 |
_c57517 _d57517 |
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