000			03264nam a22005655i 4500
001			978-3-319-06971-5
003			DE-He213
005			20200421112226.0
007			cr nn 008mamaa
008			140604s2014 gw | s |||| 0|eng d
020			_a9783319069715 _9978-3-319-06971-5
024	7		_a10.1007/978-3-319-06971-5 _2doi
050		4	_aQH324.2-324.25
072		7	_aPSA _2bicssc
072		7	_aUB _2bicssc
072		7	_aCOM014000 _2bisacsh
082	0	4	_a570.285 _223
100	1		_aMrozek, Dariusz. _eauthor.
245	1	0	_aHigh-Performance Computational Solutions in Protein Bioinformatics _h[electronic resource] / _cby Dariusz Mrozek.
264		1	_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2014.
300			_aXIX, 109 p. 56 illus., 21 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aSpringerBriefs in Computer Science, _x2191-5768
505	0		_aFormal Model of 3D Protein Structures for Functional Genomics, Comparative Bioinformatics, and Molecular Modeling -- Multithreaded PSS-SQL for Searching Databases of Secondary Structures -- GPU and CUDA for 3D Protein Structure Similarity Searching -- Cloud Computing for 3D Protein Structure Alignment -- General Discussion and Concluding Remarks.
520			_aRecent developments in computer science enable algorithms previously perceived as too time-consuming to now be efficiently used for applications in bioinformatics and life sciences. This work focuses on proteins and their structures, protein structure similarity searching at main representation levels, and various techniques that can be used to accelerate similarity searches. Divided into four parts, the first part provides a formal model of 3D protein structures for functional genomics, comparative bioinformatics, and molecular modeling. The second part focuses on the use of multithreading for efficient approximate searching on protein secondary structures. The third and fourth parts concentrate on finding 3D protein structure similarities with the support of GPUs and cloud computing. Parts three and four both describe the acceleration of different methods. The text will be of interest to researchers and software developers working in the field of structural bioinformatics and biomedical databases.
650		0	_aComputer science.
650		0	_aMicroprocessors.
650		0	_aComputer communication systems.
650		0	_aBioinformatics.
650		0	_aProteins.
650		0	_aBiomathematics.
650	1	4	_aComputer Science.
650	2	4	_aComputational Biology/Bioinformatics.
650	2	4	_aComputer Communication Networks.
650	2	4	_aProtein Structure.
650	2	4	_aBioinformatics.
650	2	4	_aProcessor Architectures.
650	2	4	_aMathematical and Computational Biology.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783319069708
830		0	_aSpringerBriefs in Computer Science, _x2191-5768
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-319-06971-5
912			_aZDB-2-SCS
942			_cEBK
999			_c57702 _d57702