| 000 | 02906cam a2200277Ii 4500 | ||
|---|---|---|---|
| 001 | 9780429132292 | ||
| 008 | 180331s2011 fluad ob 001 0 eng d | ||
| 020 |
_a9780429132292 _q(e-book : PDF) |
||
| 020 |
_z9781439804773 _q(hardback) |
||
| 020 |
_z9781138114586 _q(paperback) |
||
| 024 | 7 |
_a10.1201/b10845 _2doi |
|
| 035 | _a(OCoLC)721195032 | ||
| 050 | 4 |
_aRL801 _b.D47 2011 |
|
| 082 | 0 | 4 |
_a615.778 _bD435 |
| 245 | 0 | 0 |
_aDermatokinetics of therapeutic agents / _cedited by S. Narasimha Murthy. |
| 264 | 1 |
_aBoca Raton : _bCRC Press, _c2011. |
|
| 300 | _a1 online resource (xii, 207 pages) | ||
| 505 | 0 | _ach. 1. Introduction to dermatokinetics / Ya-Ting Wu, Yuri G. Anissimov, and Michael S. Roberts -- ch. 2. Theoretical models for dermatokinetics of therapeutic agents / Rong Shi and Hartmut Derendorf -- ch. 3. Formulation approaches to modulate the dermatokinetics of drugs / Srinivasa Murthy Sammeta, Michael A. Repka, and S. Narasimha Murthy -- ch. 4. Conventional methods of cutaneous drug sampling / Jose Juan Escobar-Chavez, Miriam Lopez-Cervantes, and Adriana Ganem Rondero -- ch. 5. Cutaneous microdialysis / Grazia Stagni --ch. 6. Sampling substrates by skin permeabilization / M. Begona Delgado-Charro -- ch. 7. Spectroscopic techniques in dermatokinetic studies / Georgios N. Stamatas -- ch. 8. Regulatory perspective of dermatokinetic studies / April C. Braddy and Dale P. Conner. | |
| 520 | _aNovel drug delivery technologies strive to bypass challenging biological layers to elicit desired pharmacological activity. The skin, one of our key defensive barriers, is imperfect, and may allow certain topically applied substances or toxins to pass. The dermatokinetics of a drug determines the efficacy of treatment of skin disorders. Presenting the first comprehensive reference on this important area of research, Dermatokinetics of Therapeutic Agents includes a general overview of the theoretical as well as practical aspects of dermatokinetics and addresses the impact of nature of a drug delivery system on the dermatokinetics of drugs. Chapters and illustrations cover the introductory aspects significance, methods, and models used in dermatokinetic studies of therapeutic agents.Topics include: Theoretical Models for Dermatokinetics of Therapeutic Agents; Drug Delivery Approaches to Modulate Dermatokinetics of Drugs; Conventional Methods of Cutaneous Drug Sampling; Cutaneous Microdialysis; Sampling Substrates by Skin Permeabilization; Spectroscopic Techniques in Dermatokinetics Studies; Regulatory Perspective of Dermatokinetic Studies--Provided by publisher. | ||
| 650 | 0 |
_aDermatologic agents. _915430 |
|
| 650 | 0 |
_aPharmacokinetics. _915431 |
|
| 700 | 1 |
_aMurthy, S. Narasimha _q(Sathyanarayana Narasimha), _d1971- _915432 |
|
| 776 | 0 | 8 |
_iPrint version: _z9781439804773 |
| 856 | 4 | 0 |
_uhttps://www.taylorfrancis.com/books/9781439804780 _zClick here to view. |
| 942 | _cEBK | ||
| 999 |
_c70980 _d70980 |
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