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020 _a9783030017750
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024 7 _a10.1007/978-3-030-01775-0
_2doi
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072 7 _aTEC059000
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072 7 _aMQW
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082 0 4 _a610.28
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245 1 0 _aNanotheranostics for Cancer Applications
_h[electronic resource] /
_cedited by Prakash Rai, Stephanie A. Morris.
250 _a1st ed. 2019.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2019.
300 _aXIV, 480 p. 89 illus., 83 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
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490 1 _aBioanalysis, Advanced Materials, Methods, and Devices,
_x2364-1126 ;
_v5
505 0 _aAbout the Editors -- List of Contributors -- Part I Introduction to Cancer and Nanotechnology -- 1 Introduction -- 2 Biological Events and Barriers to Effective Delivery of Cancer Therapeutics -- 3 Cancer Diagnostics and Therapeutics -- 4 Nanomedicine in Cancer -- 5 Theranostics: A Historical Perspective of Cancer Nanotechnology Paving the Way for Simultaneous Use Applications -- Part II Cancer Nanodiagnostics and Nanotherapeutics -- 6 In Vitro Cancer Diagnostics -- 7 Translational Nanodiagnostics for In Vivo Cancer Detection -- 8 Delivery of Cancer Nanotherapeutics -- 9 Oral Nanotherapeutics for Cancer with Innovations in Lipid and Polymeric Nanoformulations -- 10 Topical and Transdermal Nanomedicines for Cancer Therapy -- 11 Cancer Nanotherapeutics Administered by Non-Conventional Routes -- Part III Regulatory Considerations for Nanomaterial Drug Products -- 12 Regulatory Considerations for Cancer Drug Products Containing Nanomaterials -- 13 Perspectives for Characterizing Drug Component of Theranostic Products Containing Nanomaterials -- Part IV Cancer Nanotheranostics -- 14 Engineering Multifunctional Nanomedicine Platforms for Drug Delivery and Imaging -- 15 Image-Guided Drug Delivery -- 16 Nanotheranostics-Based Imaging for Cancer Treatment Monitoring -- 17 Remotely-Triggered Nanotheranostics -- 18 Concluding Remarks and the Future of Nanotheranostics -- Index.
520 _aThis book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics. Provides a comprehensive review of cancer nanotheranostics Represents the first book-length treatment of the topic Presents a full picture of the field, from basic research through clinical implementation Features evidence-based chapters with excellent illustrations and images to guide and assist the reader.
650 0 _aBiomedical engineering.
_93292
650 0 _aOncology.
_936075
650 0 _aNanochemistry.
_911788
650 0 _aBiomaterials.
_916365
650 0 _aPharmaceutical chemistry.
_912688
650 0 _aBiophysics.
_94093
650 1 4 _aBiomedical Engineering and Bioengineering.
_931842
650 2 4 _aOncology.
_936075
650 2 4 _aNanochemistry.
_911788
650 2 4 _aBiomaterials.
_916365
650 2 4 _aPharmaceutics.
_935916
650 2 4 _aBiophysics.
_94093
700 1 _aRai, Prakash.
_eeditor.
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_4http://id.loc.gov/vocabulary/relators/edt
_936076
700 1 _aMorris, Stephanie A.
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_936077
710 2 _aSpringerLink (Online service)
_936078
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783030017736
776 0 8 _iPrinted edition:
_z9783030017743
830 0 _aBioanalysis, Advanced Materials, Methods, and Devices,
_x2364-1126 ;
_v5
_936079
856 4 0 _uhttps://doi.org/10.1007/978-3-030-01775-0
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