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020 _a9783030499006
_9978-3-030-49900-6
024 7 _a10.1007/978-3-030-49900-6
_2doi
050 4 _aTA352-356
050 4 _aQC20.7.N6
072 7 _aTBJ
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082 0 4 _a515.39
_223
100 1 _aGomez-Pilar, Javier.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_940546
245 1 0 _aCharacterization of Neural Activity Using Complex Network Theory
_h[electronic resource] :
_bAn Application to the Study of Schizophrenia /
_cby Javier Gomez-Pilar.
250 _a1st ed. 2021.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2021.
300 _aXVIII, 67 p. 24 illus., 19 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringer Theses, Recognizing Outstanding Ph.D. Research,
_x2190-5061
505 0 _aIntroduction -- Hypotheses and objectives -- 3 Materials and methods -- Results -- Discussion.
520 _aThis book reports on the development and assessment of a novel framework for studying neural interactions (the connectome) and their dynamics (the chronnectome). Using EEG recordings taken during an auditory oddball task performed by 48 patients with schizophrenia and 87 healthy controls, and applying local and network measures, changes in brain activation from pre-stimulus to cognitive response were assessed, and significant differences were observed between the patients and controls. This book investigates the source of the network abnormalities and presents new evidence for the disconnection hypothesis and the aberrant salience hypothesis with regard to schizophrenia. Moreover, it puts forward a novel approach to combining local regularity measures and graph measures in order to characterize schizophrenia brain dynamics, and presents interesting findings on the regularity of brain patterns in healthy control subjects versus patients with schizophrenia. Besides providing new evidence for the disconnection hypothesis, it offers a source of inspiration for future research directions in the field.
650 0 _aDynamics.
_940547
650 0 _aNonlinear theories.
_93339
650 0 _aComputational neuroscience.
_915392
650 0 _aGraph theory.
_93662
650 1 4 _aApplied Dynamical Systems.
_932005
650 2 4 _aComputational Neuroscience.
_915392
650 2 4 _aGraph Theory.
_93662
710 2 _aSpringerLink (Online service)
_940548
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783030498993
776 0 8 _iPrinted edition:
_z9783030499013
776 0 8 _iPrinted edition:
_z9783030499020
830 0 _aSpringer Theses, Recognizing Outstanding Ph.D. Research,
_x2190-5061
_940549
856 4 0 _uhttps://doi.org/10.1007/978-3-030-49900-6
912 _aZDB-2-ENG
912 _aZDB-2-SXE
942 _cEBK
999 _c76767
_d76767