000 | 04382nam a22006855i 4500 | ||
---|---|---|---|
001 | 978-981-10-2529-7 | ||
003 | DE-He213 | ||
005 | 20220801220154.0 | ||
007 | cr nn 008mamaa | ||
008 | 161104s2017 si | s |||| 0|eng d | ||
020 |
_a9789811025297 _9978-981-10-2529-7 |
||
024 | 7 |
_a10.1007/978-981-10-2529-7 _2doi |
|
050 | 4 | _aR856-857 | |
072 | 7 |
_aMQW _2bicssc |
|
072 | 7 |
_aTEC059000 _2bisacsh |
|
072 | 7 |
_aMQW _2thema |
|
082 | 0 | 4 |
_a610.28 _223 |
100 | 1 |
_aLaurent, Sophie. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut _948741 |
|
245 | 1 | 0 |
_aMRI Contrast Agents _h[electronic resource] : _bFrom Molecules to Particles / _cby Sophie Laurent, Céline Henoumont, Dimitri Stanicki, Sébastien Boutry, Estelle Lipani, Sarah Belaid, Robert N. Muller, Luce Vander Elst. |
250 | _a1st ed. 2017. | ||
264 | 1 |
_aSingapore : _bSpringer Nature Singapore : _bImprint: Springer, _c2017. |
|
300 |
_aVII, 125 p. 63 illus., 44 illus. in color. _bonline resource. |
||
336 |
_atext _btxt _2rdacontent |
||
337 |
_acomputer _bc _2rdamedia |
||
338 |
_aonline resource _bcr _2rdacarrier |
||
347 |
_atext file _bPDF _2rda |
||
490 | 1 |
_aNanotheranostics, _x2197-6759 |
|
505 | 0 | _aNanomaterials in medicine -- Magnetic properties (diamagnetism, paramagnetism, ferromagnetism, ferrimagnetism, antiferromagnetism, superparamagnetism) -- Imaging probes -- Magnetic resonance imaging (MRI) -- Bases of MRI -- MRI contrast agents -- Paramagnetic gadolinium complexes -- Superparamagnetic iron oxide nanoparticles -- Synthesis of magnetic nanoparticles -- Stabilization of magnetic nanoparticles -- Physico-chemical characterization of nanoparticles -- MRI applications -- Conclusions. | |
520 | _aThis book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc. . | ||
650 | 0 |
_aBiomedical engineering. _93292 |
|
650 | 0 |
_aBiomaterials. _916365 |
|
650 | 0 |
_aMicrotechnology. _928219 |
|
650 | 0 |
_aMicroelectromechanical systems. _96063 |
|
650 | 0 |
_aMedicine—Research. _936667 |
|
650 | 0 |
_aBiology—Research. _936668 |
|
650 | 0 |
_aMedical physics. _94451 |
|
650 | 1 | 4 |
_aBiomedical Engineering and Bioengineering. _931842 |
650 | 2 | 4 |
_aBiomaterials. _916365 |
650 | 2 | 4 |
_aMicrosystems and MEMS. _948742 |
650 | 2 | 4 |
_aBiomedical Research. _936670 |
650 | 2 | 4 |
_aMedical Physics. _94451 |
700 | 1 |
_aHenoumont, Céline. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut _948743 |
|
700 | 1 |
_aStanicki, Dimitri. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut _948744 |
|
700 | 1 |
_aBoutry, Sébastien. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut _948745 |
|
700 | 1 |
_aLipani, Estelle. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut _948746 |
|
700 | 1 |
_aBelaid, Sarah. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut _948747 |
|
700 | 1 |
_aMuller, Robert N. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut _948748 |
|
700 | 1 |
_aVander Elst, Luce. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut _948749 |
|
710 | 2 |
_aSpringerLink (Online service) _948750 |
|
773 | 0 | _tSpringer Nature eBook | |
776 | 0 | 8 |
_iPrinted edition: _z9789811025273 |
776 | 0 | 8 |
_iPrinted edition: _z9789811025280 |
830 | 0 |
_aNanotheranostics, _x2197-6759 _948751 |
|
856 | 4 | 0 | _uhttps://doi.org/10.1007/978-981-10-2529-7 |
912 | _aZDB-2-ENG | ||
912 | _aZDB-2-SXE | ||
942 | _cEBK | ||
999 |
_c78281 _d78281 |