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020 _a9783319722450
_9978-3-319-72245-0
024 7 _a10.1007/978-3-319-72245-0
_2doi
050 4 _aR856-857
072 7 _aMQW
_2bicssc
072 7 _aTEC059000
_2bisacsh
072 7 _aMQW
_2thema
082 0 4 _a610.28
_223
100 1 _aCinar, Ali.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_953004
245 1 0 _aAdvances in Artificial Pancreas Systems
_h[electronic resource] :
_bAdaptive and Multivariable Predictive Control /
_cby Ali Cinar, Kamuran Turksoy.
250 _a1st ed. 2018.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2018.
300 _aXII, 119 p. 22 illus., 9 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringerBriefs in Bioengineering,
_x2193-0988
505 0 _aIntroduction -- Physiology and Factors Affecting Blood Glucose Concentration -- Components of an Artificial Pancreas -- Modeling Glucose Concentration Dynamics -- Hypoglycemia Alarm Systems -- Hyperglycemia Alarm Systems -- Various Control Philosophies and Algorithms -- Multivariable Control of Glucose Concentration -- Dual Hormone Techniques for AP Systems -- Integrated Hypo-/Hyperglycemia Alarm and Control Systems -- Future Developments.
520 _aThis brief introduces recursive modeling techniques that take account of variations in blood glucose concentration within and between individuals. It describes their use in developing multivariable models in early-warning systems for hypo- and hyperglycemia; these models are more accurate than those solely reliant on glucose and insulin concentrations because they can accommodate other relevant influences like physical activity, stress and sleep. Such factors also contribute to the accuracy of the adaptive control systems present in the artificial pancreas which is the focus of the brief, as their presence is indicated before they have an apparent effect on the glucose concentration and so can be more easily compensated. The adaptive controller is based on generalized predictive control techniques and also includes rules for changing controller parameters or structure based on the values of physiological variables. Simulation studies and clinical studies are reported to illustrate the performance of the techniques presented.
650 0 _aBiomedical engineering.
_93292
650 0 _aControl engineering.
_931970
650 0 _aEndocrinology.
_953005
650 1 4 _aBiomedical Engineering and Bioengineering.
_931842
650 2 4 _aControl and Systems Theory.
_931972
650 2 4 _aEndocrinology.
_953005
700 1 _aTurksoy, Kamuran.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_953006
710 2 _aSpringerLink (Online service)
_953007
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319722443
776 0 8 _iPrinted edition:
_z9783319722467
830 0 _aSpringerBriefs in Bioengineering,
_x2193-0988
_953008
856 4 0 _uhttps://doi.org/10.1007/978-3-319-72245-0
912 _aZDB-2-ENG
912 _aZDB-2-SXE
942 _cEBK
999 _c79064
_d79064