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001 978-3-319-58845-2
003 DE-He213
005 20220801221803.0
007 cr nn 008mamaa
008 170620s2018 sz | s |||| 0|eng d
020 _a9783319588452
_9978-3-319-58845-2
024 7 _a10.1007/978-3-319-58845-2
_2doi
050 4 _aTA349-359
072 7 _aTGMD
_2bicssc
072 7 _aSCI096000
_2bisacsh
072 7 _aTGMD
_2thema
082 0 4 _a620.105
_223
245 1 0 _aMultiscale Mechanobiology of Bone Remodeling and Adaptation
_h[electronic resource] /
_cedited by Peter Pivonka.
250 _a1st ed. 2018.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2018.
300 _aXII, 287 p. 98 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCISM International Centre for Mechanical Sciences, Courses and Lectures,
_x2309-3706 ;
_v578
505 0 _aBone cell biology and mechanobiology -- Disease systems analysis of osteoporosis and treatments -- Bone quality assessment across the scales -- Interaction of bone tissue with other tissues including muscle, cartilage, and vascularization -- Musculoskeletal modeling of human movement -- Image-based 3D micro-FE modeling.
520 _aThe book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.
650 0 _aMechanics, Applied.
_93253
650 0 _aSolids.
_93750
650 0 _aBiomaterials.
_916365
650 0 _aOrthopedics.
_933754
650 1 4 _aSolid Mechanics.
_931612
650 2 4 _aBiomaterials.
_916365
650 2 4 _aOrthopaedics.
_933757
700 1 _aPivonka, Peter.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_957989
710 2 _aSpringerLink (Online service)
_957990
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319588438
776 0 8 _iPrinted edition:
_z9783319588445
776 0 8 _iPrinted edition:
_z9783319864891
830 0 _aCISM International Centre for Mechanical Sciences, Courses and Lectures,
_x2309-3706 ;
_v578
_957991
856 4 0 _uhttps://doi.org/10.1007/978-3-319-58845-2
912 _aZDB-2-ENG
912 _aZDB-2-SXE
942 _cEBK
999 _c80052
_d80052