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| 001 | 978-3-662-49118-8 | ||
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| 007 | cr nn 008mamaa | ||
| 008 | 160121s2016 gw | s |||| 0|eng d | ||
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_a10.1007/978-3-662-49118-8 _2doi |
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_aEssentials of Single-Cell Analysis _h[electronic resource] : _bConcepts, Applications and Future Prospects / _cedited by Fan-Gang Tseng, Tuhin Subhra Santra. |
| 250 | _a1st ed. 2016. | ||
| 264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2016. |
|
| 300 |
_aX, 414 p. 142 illus., 15 illus. in color. _bonline resource. |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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_atext file _bPDF _2rda |
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| 490 | 1 |
_aSeries in BioEngineering, _x2196-887X |
|
| 505 | 0 | _aSingle Cell Behavioral Assays for Heterogeneity Studies -- Systems biology in single cells -- Electroporation for single cell analysis -- Microinjection for single cell analysis -- Optical tools for single cell manipulation and analysis -- Optoelectrokinetic manipulation for cell analysis -- Continuous micro/nano-fluidic devices for single cell analysis -- Single Cell Mechanical Properties: Label-Free Biomarkers for Cell Status Evaluation -- Cytometry of single cells for biology and biomedicine -- Single cell genomics and epigenomics -- Single cell Metabolomics -- Applications of cell based drug delivery systems: use of single cell assay -- Applications of Single Cell Sequencing in Cancer -- Single Cell Characterization of Microalgal Lipid Contents with Confocal Raman Microscopy -- Single Differentiated Neurons from Pluripotent Embryonic Stem Cells: Motor Protein Modelling and Neurodegenerative Disease. | |
| 520 | _aThis book provides an overview of single-cell isolation, separation, injection, lysis and dynamics analysis as well as a study of their heterogeneity using different miniaturized devices. As an important part of single-cell analysis, different techniques including electroporation, microinjection, optical trapping, optoporation, rapid electrokinetic patterning and optoelectronic tweezers are described in detail. It presents different fluidic systems (e.g. continuous micro/nano-fluidic devices, microfluidic cytometry) and their integration with sensor technology, optical and hydrodynamic stretchers etc., and demonstrates the applications of single-cell analysis in systems biology, proteomics, genomics, epigenomics, cancer transcriptomics, metabolomics, biomedicine and drug delivery systems. It also discusses the future challenges for single-cell analysis, including the advantages and limitations. This book is enjoyable reading material while at the same time providing essential information to scientists in academia and professionals in industry working on different aspects of single-cell analysis. Dr. Fan-Gang Tseng is a Distinguished Professor of Engineering and System Science at the National Tsing Hua University, Taiwan. Dr. Tuhin Subhra Santra is a Research Associate at the California Nano Systems Institute, University of California at Los Angeles, USA. | ||
| 650 | 0 |
_aBiomedical engineering. _93292 |
|
| 650 | 0 |
_aMicrotechnology. _928219 |
|
| 650 | 0 |
_aMicroelectromechanical systems. _96063 |
|
| 650 | 0 |
_aBioinformatics. _99561 |
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| 650 | 0 |
_aBiophysics. _94093 |
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| 650 | 0 |
_aCytology. _934308 |
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| 650 | 1 | 4 |
_aBiomedical Engineering and Bioengineering. _931842 |
| 650 | 2 | 4 |
_aMicrosystems and MEMS. _958277 |
| 650 | 2 | 4 |
_aBioinformatics. _99561 |
| 650 | 2 | 4 |
_aBiophysics. _94093 |
| 650 | 2 | 4 |
_aCell Biology. _934309 |
| 700 | 1 |
_aTseng, Fan-Gang. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt _958278 |
|
| 700 | 1 |
_aSantra, Tuhin Subhra. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt _958279 |
|
| 710 | 2 |
_aSpringerLink (Online service) _958280 |
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| 773 | 0 | _tSpringer Nature eBook | |
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_iPrinted edition: _z9783662491164 |
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_iPrinted edition: _z9783662491171 |
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_iPrinted edition: _z9783662569801 |
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_aSeries in BioEngineering, _x2196-887X _958281 |
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| 856 | 4 | 0 | _uhttps://doi.org/10.1007/978-3-662-49118-8 |
| 912 | _aZDB-2-ENG | ||
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