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001 978-3-319-54253-9
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005 20220801222231.0
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008 170315s2017 sz | s |||| 0|eng d
020 _a9783319542539
_9978-3-319-54253-9
024 7 _a10.1007/978-3-319-54253-9
_2doi
050 4 _aR856-857
072 7 _aMQW
_2bicssc
072 7 _aTEC059000
_2bisacsh
072 7 _aMQW
_2thema
082 0 4 _a610.28
_223
100 1 _aMitra, Kunal.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_960413
245 1 0 _aShort Pulse Laser Systems for Biomedical Applications
_h[electronic resource] /
_cby Kunal Mitra, Stephanie Miller.
250 _a1st ed. 2017.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2017.
300 _aVII, 49 p. 26 illus., 9 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringerBriefs in Applied Sciences and Technology,
_x2191-5318
505 0 _aIntroduction -- Short Pulse Laser Imaging -- Short Pulse Laser Based Thermal Therapy -- Use of Nanoparticles to Optimize Short Pulse Laser Based Biomedical Applications.
520 _aThis book presents practical information on the clinical applications of short pulse laser systems and the techniques for optimizing these applications in a manner that will be relevant to a broad audience, including engineering and medical students as well as researchers, clinicians, and technicians. Short pulse laser systems are useful for both subsurface tissue imaging and laser induced thermal therapy (LITT), which hold great promise in cancer diagnostics and treatment. Such laser systems may be used alone or in combination with optically active nanoparticles specifically administered to the tissues of interest for enhanced contrast in imaging and precise heating during LITT. Mathematical and computational models of short pulse laser-tissue interactions that consider the transient radiative transport equation coupled with a bio-heat equation considering the initial transients of laser heating were developed to analyze the laser-tissue interaction during imaging and therapy. Experiments were first performed to characterize the tissue optical properties needed to optimize the dose for thermal therapy. Experiments were then performed on animal models to characterize the heat affected zone for LITT. The experimental measurements were also validated using the computational models. .
650 0 _aBiomedical engineering.
_93292
650 0 _aBiotechnology.
_97533
650 0 _aLasers.
_97879
650 0 _aCancer.
_915213
650 0 _aMicrotechnology.
_928219
650 0 _aMicroelectromechanical systems.
_96063
650 1 4 _aBiomedical Engineering and Bioengineering.
_931842
650 2 4 _aBiotechnology.
_97533
650 2 4 _aLaser.
_931624
650 2 4 _aCancer Biology.
_936669
650 2 4 _aMicrosystems and MEMS.
_960414
700 1 _aMiller, Stephanie.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_960415
710 2 _aSpringerLink (Online service)
_960416
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319542522
776 0 8 _iPrinted edition:
_z9783319542546
830 0 _aSpringerBriefs in Applied Sciences and Technology,
_x2191-5318
_960417
856 4 0 _uhttps://doi.org/10.1007/978-3-319-54253-9
912 _aZDB-2-ENG
912 _aZDB-2-SXE
942 _cEBK
999 _c80542
_d80542