| 000 | 05707nam a2200817 i 4500 | ||
|---|---|---|---|
| 001 | 9780750335676 | ||
| 003 | IOP | ||
| 005 | 20230516170239.0 | ||
| 006 | m eo d | ||
| 007 | cr cn |||m|||a | ||
| 008 | 210805s2021 enka fob 000 0 eng d | ||
| 020 |
_a9780750335676 _qebook |
||
| 020 |
_a9780750335669 _qmobi |
||
| 020 |
_z9780750335652 _qprint |
||
| 020 |
_z9780750335683 _qmyPrint |
||
| 024 | 7 |
_a10.1088/978-0-7503-3567-6 _2doi |
|
| 035 | _a(CaBNVSL)thg00082571 | ||
| 035 | _a(OCoLC)1262946075 | ||
| 040 |
_aCaBNVSL _beng _erda _cCaBNVSL _dCaBNVSL |
||
| 050 | 4 |
_aQM411 _b.M543 2021eb |
|
| 060 | 4 |
_aWJ 500 _bM633b 2021eb |
|
| 072 | 7 |
_aMQW _2bicssc |
|
| 072 | 7 |
_aTEC059000 _2bisacsh |
|
| 082 | 0 | 4 |
_a612.4/673 _23 |
| 100 | 1 |
_aMiftahof, Roustem N., _eauthor. _970462 |
|
| 245 | 1 | 4 |
_aThe brain-bladder axis in tissue growth and remodelling / _cRoustem N. Miftahof and Christian J. Cyron. |
| 264 | 1 |
_aBristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : _bIOP Publishing, _c[2021] |
|
| 300 |
_a1 online resource (various pagings) : _billustrations (some color). |
||
| 336 |
_atext _2rdacontent |
||
| 337 |
_aelectronic _2isbdmedia |
||
| 338 |
_aonline resource _2rdacarrier |
||
| 490 | 1 | _a[IOP release $release] | |
| 490 | 1 | _aIPEM-IOP series in physics and engineering in medicine and biology | |
| 490 | 1 | _aIOP ebooks. [2021 collection] | |
| 500 | _a"Version: 20210207"--Title page verso. | ||
| 504 | _aIncludes bibliographical references. | ||
| 505 | 0 | _a1. Anatomical and morphological preliminaries -- 1.1. Overview of the urinary bladder -- 1.2. Detrusor muscle -- 1.3. 'Pacemakers' -- 1.4. Mechanosensation -- 1.5. Afferent signalling -- 1.6. Neuronal assemblies in the hypothalamus and adenohypophysis | |
| 505 | 8 | _a2. Continual models of the bladder tissue -- 2.1. Single-phase models -- 2.2. Multiphase models | |
| 505 | 8 | _a3. Models of the urinary bladder -- 3.1. The bladder as shell structure -- 3.2. The bladder as soft bioshell | |
| 505 | 8 | _a4. Signalling mechanisms -- 4.1. L-Glutamate -- 4.2. GABA -- 4.3. Glycine -- 4.4. Somatostatin -- 4.5. Growth hormone releasing hormone -- 4.6. Ghrelin -- 4.7. Growth hormone -- 4.8. Insulin-like growth factor-1 -- 4.9. Myogenesis -- 4.10. Collagenesis | |
| 505 | 8 | _a5. Modelling the (intra)hypothalamic-pituitary axis -- 5.1. Signal transduction -- 5.2. Protein-tyrosine kinase receptor signalling -- 5.3. Gene expression -- 5.4. Hormonal interactions | |
| 505 | 8 | _a6. Growth and remodelling -- 6.1. Biological preliminaries -- 6.2. Continuum mechanics growth and remodelling models | |
| 505 | 8 | _a7. Brain-bladder axis in tissue growth and remodelling -- 7.1. The architecture of the BBA -- 7.2. Mathematical formulation of the BBA -- 7.3. An Achilles' heel -- 7.4. Simulation results | |
| 505 | 8 | _a8. What is to follow? -- 8.1. Making a model reliable -- 8.2. Model expansions in biomedicine -- 8.3. Implementations in engineering. | |
| 520 | 3 | _aApplying the general deterministic approach of systems computational biology, the monograph considers questions related to the biomechanics of the human urinary bladder in conjunction with the peripheral and central nervous systems. The step-by-step development of mathematical models of separate structural elements and their assembly into a unique self-regulatory system offers, for the first time, a holistic overview and allows the investigation of the dynamics of the lower urinary tract system at its hierarchical levels. This book provides a coherent description and explanation for intertwined intracellular pathways in terms of spatiotemporal, whole body, tractable representations which are supported by numerous computational simulations. | |
| 521 | _aAcademic, Research and Industrial Scientists. The prerequisites to the book are a familiarity with the basic principles of cell and molecular biology, biochemistry and the mechanics of solids. | ||
| 530 | _aAlso available in print. | ||
| 538 | _aMode of access: World Wide Web. | ||
| 538 | _aSystem requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader. | ||
| 545 | _aProf. Dr. R.N. Miftahoft is a Professor Emeritus of applied mathematics and medicine. He is internationally acclaimed as a leading scientist in the field of computational systems biology. He has authored and co-authored seven books in the field. Prof. Dr-Ing. C.J. Cyron is a Full Professor at Hamburg University of Technology and has actively participated in the organization of a host of conferences, workshops and summer schools on biomechanics and mechanobiology over a number of years. | ||
| 588 | 0 | _aTitle from PDF title page (viewed on August 5, 2021). | |
| 650 | 0 |
_aBladder _xGrowth _xMathematical models. _970463 |
|
| 650 | 0 |
_aBladder _xInnervation _xMathematical models. _970464 |
|
| 650 | 0 |
_aTissue remodeling _xMathematical models. _970465 |
|
| 650 | 0 |
_aNeurobiology. _923097 |
|
| 650 | 1 | 2 |
_aUrinary Bladder _xphysiology. _970466 |
| 650 | 1 | 2 |
_aUrinary Bladder _xinnervation. _970467 |
| 650 | 1 | 2 |
_aRegeneration. _968655 |
| 650 | 2 | 2 |
_aModels, Theoretical. _921565 |
| 650 | 2 | 2 |
_aNeurobiology. _923097 |
| 650 | 7 |
_aBiomedical engineering. _2bicssc _93292 |
|
| 650 | 7 |
_aMedical physics and biophysics. _2bisacsh _970121 |
|
| 700 | 1 |
_aCyron, Christian J., _eauthor. _970468 |
|
| 710 | 2 |
_aInstitute of Physics (Great Britain), _epublisher. _911622 |
|
| 776 | 0 | 8 |
_iPrint version: _z9780750335652 _z9780750335683 |
| 830 | 0 |
_aIOP (Series). _pRelease 21. _970469 |
|
| 830 | 0 |
_aIPEM-IOP series in physics and engineering in medicine and biology. _970161 |
|
| 830 | 0 |
_aIOP ebooks. _p2021 collection. _970470 |
|
| 856 | 4 | 0 | _uhttps://iopscience.iop.org/book/978-0-7503-3567-6 |
| 942 | _cEBK | ||
| 999 |
_c82844 _d82844 |
||