000 03598nam a22005175i 4500
001 978-3-031-01650-9
003 DE-He213
005 20240730163645.0
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008 220601s2011 sz | s |||| 0|eng d
020 _a9783031016509
_9978-3-031-01650-9
024 7 _a10.1007/978-3-031-01650-9
_2doi
050 4 _aT1-995
072 7 _aTBC
_2bicssc
072 7 _aTEC000000
_2bisacsh
072 7 _aTBC
_2thema
082 0 4 _a620
_223
100 1 _aNalbantoglu, Ozkan Ufuk.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_979770
245 1 0 _aComputational Genomic Signatures
_h[electronic resource] /
_cby Ozkan Ufuk Nalbantoglu, Khalid Sayood.
250 _a1st ed. 2011.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2011.
300 _aXVI, 113 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSynthesis Lectures on Biomedical Engineering,
_x1930-0336
505 0 _aGenome Signatures, Definition and Background -- Other Computational Characterizations as Genome Signatures -- Measuring Distance of Biological Sequences Using Genome Signatures -- Applications: Phylogeny Construction -- Applications: Metagenomics -- Applications: Horizontal DNA Transfer Detection.
520 _aRecent advances in development of sequencing technology has resulted in a deluge of genomic data. In order to make sense of this data, there is an urgent need for algorithms for data processing and quantitative reasoning. An emerging in silico approach, called computational genomic signatures, addresses this need by representing global species-specific features of genomes using simple mathematical models. This text introduces the general concept of computational genomic signatures, and it reviews some of the DNA sequence models which can be used as computational genomic signatures. The text takes the position that a practical computational genomic signature consists of both a model and a measure for computing the distance or similarity between models. Therefore, a discussion of sequence similarity/distance measurement in the context of computational genomic signatures is presented. The remainder of the text covers various applications of computational genomic signatures in the areas ofmetagenomics, phylogenetics and the detection of horizontal gene transfer. Table of Contents: Genome Signatures, Definition and Background / Other Computational Characterizations as Genome Signatures / Measuring Distance of Biological Sequences Using Genome Signatures / Applications: Phylogeny Construction / Applications: Metagenomics / Applications: Horizontal DNA Transfer Detection.
650 0 _aEngineering.
_99405
650 0 _aBiophysics.
_94093
650 0 _aBiomedical engineering.
_93292
650 1 4 _aTechnology and Engineering.
_979771
650 2 4 _aBiophysics.
_94093
650 2 4 _aBiomedical Engineering and Bioengineering.
_931842
700 1 _aSayood, Khalid.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_979772
710 2 _aSpringerLink (Online service)
_979773
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031005220
776 0 8 _iPrinted edition:
_z9783031027789
830 0 _aSynthesis Lectures on Biomedical Engineering,
_x1930-0336
_979774
856 4 0 _uhttps://doi.org/10.1007/978-3-031-01650-9
912 _aZDB-2-SXSC
942 _cEBK
999 _c84845
_d84845