000 05625nam a22005175i 4500
001 978-3-031-01663-9
003 DE-He213
005 20240730164901.0
007 cr nn 008mamaa
008 220601s2015 sz | s |||| 0|eng d
020 _a9783031016639
_9978-3-031-01663-9
024 7 _a10.1007/978-3-031-01663-9
_2doi
050 4 _aT1-995
072 7 _aTBC
_2bicssc
072 7 _aTEC000000
_2bisacsh
072 7 _aTBC
_2thema
082 0 4 _a620
_223
100 1 _aGhahari, Alireza.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_986512
245 1 0 _aModels of Horizontal Eye Movements
_h[electronic resource] :
_bPart 4, A Multiscale Neuron and Muscle Fiber-Based Linear Saccade Model /
_cby Alireza Ghahari, John D. Enderle.
250 _a1st ed. 2015.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2015.
300 _aXIII, 108 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSynthesis Lectures on Biomedical Engineering,
_x1930-0336
505 0 _aAcknowledgments -- A New Linear Muscle Fiber Model for Neural Control of Saccades\footnotemark -- A Physiological Neural Controller of a Muscle Fiber Oculomotor Plant in Horizontal Monkey Saccades\footnotemark -- References -- Authors' Biographies .
520 _aThere are five different types of eye movements: saccades, smooth pursuit, vestibular ocular eye movements, optokinetic eye movements, and vergence eye movements. The purpose of this book series is focused primarily on mathematical models of the horizontal saccadic eye movement system and the smooth pursuit system, rather than on how visual information is processed. In Part 1, early models of saccades and smooth pursuit are presented. A number of oculomotor plant models are described here beginning with the Westheimer model published in 1954, and up through our 1995 model involving a 4th order oculomotor plant model. In Part 2, a 2009 version of a state-of-the-art model is presented for horizontal saccades that is 3rd-order and linear, and controlled by a physiologically based time-optimal neural network. Part 3 describes a model of the saccade system, focusing on the neural network. It presents a neural network model of biophysical neurons in the midbrain for controlling oculomotor muscles during horizontal human saccades. In this book, a multiscale model of the saccade system is presented, focusing on a multiscale neural network and muscle fiber model. Chapter 1 presents a comprehensive model for the control of horizontal saccades using a muscle fiber model for the lateral and medial rectus muscles. The importance of this model is that each muscle fiber has a separate neural input. This model is robust and accounts for the neural activity for both large and small saccades. The muscle fiber model consists of serial sequences of muscle fibers in parallel with other serial sequences of muscle fibers. Each muscle fiber is described by a parallel combination of a linear length tension element, viscous element, and active-state tension generator. Chapter 2 presents a biophysically realistic neural network model in the midbrain to drive a muscle fiber oculomotor plant during horizontal monkey saccades. Neural circuitry, including omnipause neuron, premotor excitatory andinhibitory burst neurons, long lead burst neuron, tonic neuron, interneuron, abducens nucleus, and oculomotor nucleus, is developed to examine saccade dynamics. The time-optimal control mechanism demonstrates how the neural commands are encoded in the downstream saccadic pathway by realization of agonist and antagonist controller models. Consequently, each agonist muscle fiber is stimulated by an agonist neuron, while an antagonist muscle fiber is unstimulated by a pause and step from the antagonist neuron. It is concluded that the neural network is constrained by a minimum duration of the agonist pulse, and that the most dominant factor in determining the saccade magnitude is the number of active neurons for the small saccades. For the large saccades, however, the duration of agonist burst firing significantly affects the control of saccades. The proposed saccadic circuitry establishes a complete model of saccade generation since it not only includes the neural circuits at both the premotor and motor stages of the saccade generator, but it also uses a time-optimal controller to yield the desired saccade magnitude. Table of Contents: Acknowledgments / A New Linear Muscle Fiber Model for Neural Control of Saccades\footnotemark / A Physiological Neural Controller of a Muscle Fiber Oculomotor Plant in Horizontal Monkey Saccades\footnotemark / References / Authors' Biographies.
650 0 _aEngineering.
_99405
650 0 _aBiophysics.
_94093
650 0 _aBiomedical engineering.
_93292
650 1 4 _aTechnology and Engineering.
_986516
650 2 4 _aBiophysics.
_94093
650 2 4 _aBiomedical Engineering and Bioengineering.
_931842
700 1 _aEnderle, John D.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_986518
710 2 _aSpringerLink (Online service)
_986520
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031005350
776 0 8 _iPrinted edition:
_z9783031027918
830 0 _aSynthesis Lectures on Biomedical Engineering,
_x1930-0336
_986521
856 4 0 _uhttps://doi.org/10.1007/978-3-031-01663-9
912 _aZDB-2-SXSC
942 _cEBK
999 _c85968
_d85968