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020 _a9783642047442
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024 7 _a10.1007/978-3-642-04744-2
_2doi
050 4 _aQH301-705
072 7 _aPSA
_2bicssc
072 7 _aSCI086000
_2bisacsh
072 7 _aPSA
_2thema
082 0 4 _a570
_223
245 1 0 _aComparative Genomics
_h[electronic resource] :
_bInternational Workshop, RECOMB-CG 2009, Budapest, Hungary, September 27-29, 2009, Proceedings /
_cedited by Francesca D. Ciccarelli, István Miklós.
250 _a1st ed. 2009.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2009.
300 _aVIII, 241 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
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347 _atext file
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490 1 _aLecture Notes in Bioinformatics,
_x2366-6331 ;
_v5817
505 0 _aYeast Ancestral Genome Reconstructions: The Possibilities of Computational Methods -- Natural Parameter Values for Generalized Gene Adjacency -- Parking Functions, Labeled Trees and DCJ Sorting Scenarios -- Counting All DCJ Sorting Scenarios -- Minimal Conflicting Sets for the Consecutive Ones Property in Ancestral Genome Reconstruction -- Finding Nested Common Intervals Efficiently -- DCJ Median Problems on Linear Multichromosomal Genomes: Graph Representation and Fast Exact Solutions -- Rearrangement Models and Single-Cut Operations -- Aligning Two Genomic Sequences That Contain Duplications -- Inferring the Recent Duplication History of a Gene Cluster -- Pseudo Boolean Programming for Partially Ordered Genomes -- Computing the Summed Adjacency Disruption Number between Two Genomes with Duplicate Genes Using Pseudo-Boolean Optimization -- Reconstructing Histories of Complex Gene Clusters on a Phylogeny -- Co-evolutionary Models for Reconstructing Ancestral Genomic Sequences: Computational Issues and Biological Examples -- Whole-Genome Analysis of Gene Conversion Events -- A Statistically Fair Comparison of Ancestral Genome Reconstructions, Based on Breakpoint and Rearrangement Distances -- Comparative Genomics and Extensive Recombinations in Phage Communities -- Properties of Sequence Conservation in Upstream Regulatory and Protein Coding Sequences among Paralogs in Arabidopsis thaliana -- Transcription Factor Binding Probabilities in Orthologous Promoters: An Alignment-Free Approach to the Inference of Functional Regulatory Targets.
520 _aThis book constitutes the proceedings of the 7th RECOMB International Satellite Workshop on Comparative Genomics, RECOMB-CG 2009, Budapest, Hungary, in September 2009. This workshop is devoted to bringing together scientists working on all aspects of comparative genomics, from computer scientists, mathematicians and statisticians working on novel computational approaches for genome analysis and comparison, to biologists applying these computational tools to study the structure and the evolution of prokaryotic and eukaryotic genomes. The 19 papers presented were carefully reviewed and selected from 31 submissions. The papers illustrate the crucial role of comparative genomics in understanding genome function and address a broad variety of aspects, ranging from the inference of evolution in genetic regulatory networks to the divergent fates of gene and genome duplication events and to the importance of new computational approaches to unraveling the structural evolution of genomes.
650 0 _aLife sciences.
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650 0 _aBioinformatics.
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650 0 _aComputer science
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650 1 4 _aLife Sciences.
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650 2 4 _aComputational and Systems Biology.
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650 2 4 _aBioinformatics.
_99561
650 2 4 _aSymbolic and Algebraic Manipulation.
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650 2 4 _aDiscrete Mathematics in Computer Science.
_931837
700 1 _aCiccarelli, Francesca D.
_eeditor.
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700 1 _aMiklós, István.
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710 2 _aSpringerLink (Online service)
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773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
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776 0 8 _iPrinted edition:
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830 0 _aLecture Notes in Bioinformatics,
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_9125923
856 4 0 _uhttps://doi.org/10.1007/978-3-642-04744-2
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